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Chinese Science Bulletin

, Volume 42, Issue 3, pp 231–234 | Cite as

Chemotherapy of multidrug-resistant human lung cancer combined with an MDR1 ribozyme retroviral vector in an orthotopic model

  • Zhenqiang Gao
  • Zhiping Gao
  • Xifu Liu
Bulletin

Keywords

lung cancer orthotopic model MDR1 ribozyme reversal of drug resistance therapy 

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References

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    Gao, Z. Q., Gao, Z. P., Advances in multidrug resistance gene,Chin. J. Pathol. (in Chinese), 1996, (3): 185.Google Scholar
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    Gao, Z. Q., Gao, Z. P., Reversal of drug resistance in multidrug-resistant human lung cancer cells by retrovirusmediated MDR1 antisense RNA,Chin. Sci. Bull., 1996, 41(21): 1852.Google Scholar
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    Gao, Z. Q., Zhang, Z. H., Gao, Z. P., Clinical correlates of MDR1 gene expression in human lung cancer,Chin. J. Internal. Med. (in Chinese), 1996, (7): 482.Google Scholar
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    Symons, R., Self-cleavage of RNA in the replicative of small pathogens of plants and animals,TIBS, 1989, 14: 445.PubMedGoogle Scholar
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    Gao, Z. Q., Gao, Z. P., Liu, X. F., Reversal of drug sensitivity in multidrug-resistant lung cancer cells by an MDR1 ribozyme retrovirus,Chin. Sci. Bull., 1996, 41(24): 2100.Google Scholar
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    Kobayashi, H., Dorai, T., Holland, J.et al., Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme,Cancer Res., 1994, 53: 1271.Google Scholar
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    McLemore, T. L., Liu, M. C., Blacker, P.C.et al., Novel intrapulmonary model for orthotopic propagations in human lung cancers in athymic nude mice,Cancer Res., 1987, 47: 5132.PubMedGoogle Scholar

Copyright information

© Science in China Press 1997

Authors and Affiliations

  • Zhenqiang Gao
    • 1
  • Zhiping Gao
    • 1
  • Xifu Liu
    • 1
  1. 1.Department of PathologyBeijing Medical UniversityBeijingChina

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