Clinical experience with NPH insulin
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The characteristics of the five types of insulin available and the commonly accepted modes of combining these insulins are briefly reviewed.
The advantages of NPH insulin over various combinations and mixtures of protamine zinc insulin with crystalline insulin are discussed.
Emphasis is laid upon the fact that NPH insulin is somewhat less intense in action than 2:1 mixtures of regular and protamine zinc insulins and therefore larger doses are often needed. Lack of awareness of this by many physicians has led to inadequate doses of NPH insulin and fallaciously poor results.
A guide for the combination of NPH and reg-ular insulin in diabetics requiring more than 100 units of insulin is suggested.
KeywordsProtamine Regular Insulin Separate Injection Protamine Zinc Insulin Protamine Insulin
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