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Clinical experience with NPH insulin

  • Original contribution
  • Published:
The American Journal of Digestive Diseases

Abstract

  1. 1.

    The characteristics of the five types of insulin available and the commonly accepted modes of combining these insulins are briefly reviewed.

  2. 2.

    The advantages of NPH insulin over various combinations and mixtures of protamine zinc insulin with crystalline insulin are discussed.

  3. 3.

    Emphasis is laid upon the fact that NPH insulin is somewhat less intense in action than 2:1 mixtures of regular and protamine zinc insulins and therefore larger doses are often needed. Lack of awareness of this by many physicians has led to inadequate doses of NPH insulin and fallaciously poor results.

  4. 4.

    A guide for the combination of NPH and reg-ular insulin in diabetics requiring more than 100 units of insulin is suggested.

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References

  1. Gabriole, A. J. and Marble, A.: Clinical experience with a new modified protamine insulin (NPH 50), Am. J. Digest. Diseases 16:197–206, 1949

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  2. Baganz, H. M., Carfagno, S. C, Cowan, B. Y. and Dillon, E. S.: NPH insulin: Its comparison with previous insulin regimens. Am. J. Med. Sci. 222:1–6, 1951

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Authors and Affiliations

  1. Associate Visiting Physician and Physician-in-Charge Diabetic Clinic, Harlem Hospital, New York City

    S. K. Fineberg

Authors
  1. S. K. Fineberg
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Additional information

From the Metabolic Service of the Department of Medicine, Harlem Hospital, New York City, Alexander Altschul, M.D., Director.

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Fineberg, S.K. Clinical experience with NPH insulin. Amer. Jour. Dig. Dis. 21, 286–288 (1954). https://doi.org/10.1007/BF02881223

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  • DOI: https://doi.org/10.1007/BF02881223

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