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Folia Microbiologica

, Volume 21, Issue 4, pp 297–300 | Cite as

Mutants ofEmmonsia crescens — Their pathogenicity and size of adiasporesin vivo

  • M. Hejtmánek
  • J. Bárter
Article

Abstract

The pathogenicity of seven morphological mutants ofEmmonsia crescens was tested by means of intraperitoneal inoculation in mice. All mutants caused adiaspiromycosis. Adiaspores were isolated from granulomas after 2 months and their diameters were determined. Adiaspores from granulomas caused by five mutants (M-5, M-6, M-8, M-9 and M-16) were significantly smaller than adiaspores from granulomas caused by the wild strain, from which the mutants were derived. Two mutants (M-6 and M-9) produced adiaspores of the smallest diameter (130.5 and 119.9 μm) with the lowest variance of values, differing thus most from the original wild strain with adiaspores of 230.4 μm in diameter. A positive correlation was found between the size of the adiasporein vivo and growth rate of the mycelial stage ofEmmonsia crescens in vitro. The mutation characterized by the decreased growth rate of the mycelial stage is pheno-typically manifested in the adiasporic stage of the life cycle ofEmmonsia crescens, i.e. by the smaller average size of adiaspores in granulomas.

Keywords

Wild Strain Decrease Growth Rate Quantitative Marker Intraperitoneal Inoculation Morphological Mutant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1976

Authors and Affiliations

  • M. Hejtmánek
    • 1
  • J. Bárter
    • 1
  1. 1.Department of Biology, Faculty of MedicinePalacký UniversityOlomouc

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