Abstract
7-Deoxy-13-dihydrodaunomycinone was isolated from three strains ofStreptomyces coeruleorubidus. Its production was found to rise at the end of cultivation and to be stimulated by lowered aeration intensity.
Similar content being viewed by others
References
Asbell M. A., Schwartzbach E., Bullock F. J., Yesaib D. W.: Daunomycin and adriamycin metabolism via reductive glycosidic cleavage.J. Pharmacol. Exp. Ther. 182, 63 (1972).
Bachur N. R., Gee M.: Oxygen-sensitive reductive cleavage of daunorubicin and adriamycin.Fed. Proc. 31, 835 (1972).
Bachur N. R., Gee M.: Microsomal reductive glycosidase.J. Pharmacol. Exp. Ther. 197, 681 (1976).
Blumauerová M., Matějů J., Stajner K., Vaněk Z.: Studies on the production of daunomycinonederived glycosides and related metabolites inStreptomyces coeruleorubidus andStreptomyces peucettus. Folia Microbiol. 22, 275 (1977).
Bullock F. J., Brunt R. J., Asbell M. A.: Identification of new metabolites of daunomycm and adnamyoin.J. Pharmacol. Exp. Ther. 182, 70 (1972).
Marshall V. P., Reisender E. A., Wiley P. F.: Baoterial metabolism of daunomycm.J. Antibiotics 29, 966 (1976a)
Marshall V. P., Reisender E. A., Reineke L. M., Johnson J. H., Wiley P. F.: Reductive microbial conversion of anthracycline antibiotics.Biochemistry 15, 4139 (1976b).
Mauer K. H., Brunee C., Kappus G., Habfast K., Schröder U., Schulze P.: Direct analyses of daughter ions. 19th Conference on Mass Spectrometry, paper K-9. Atlanta 1971.
MoCarville M., Marshall V. P.: Partial purification and characterisation of a bacterial enzyme catalyz mg reductive cleavage of anthracychne glycosides.Biochem. Biophys. Res. Commun. 74, 331 (1977).
Wiley P. F., Marshall V. P.: Microbial conversion of anthracyohne antibiotics.J. Antibiotics 28, 838 (1975).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Matějů, J., Vokoun, J., Blumauerová, M. et al. 7-Deoxy-13-dihydrodaunomycinone in cultures ofStreptomyces coeruleorubidus . Folia Microbiol 23, 246–248 (1978). https://doi.org/10.1007/BF02876587
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02876587