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Biogenesis of streptimidone

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Abstract

The antibiotic streptimidone is formed biogenetically from seven malonate units. One of them undergoes double decarboxylation, another one is incorporated intact. Both methyl groups are of methionine origin. Degradation procedures using14C-labelled substrates are described.

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Authors and Affiliations

  1. Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences, Prague 4

    J. Cudlín, M. Půža, Z. Vanêk & R. W. Rickards

  2. Research School of Chemistry, The Australian National University, Canberra

    J. Cudlín, M. Půža, Z. Vanêk & R. W. Rickards

Authors
  1. J. Cudlín
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  2. M. Půža
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  3. Z. Vanêk
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  4. R. W. Rickards
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Dedicated to Academician Ivan Málek on the occasion of his 60th birthday

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Cudlín, J., Půža, M., Vanêk, Z. et al. Biogenesis of streptimidone. Folia Microbiol 14, 406–416 (1969). https://doi.org/10.1007/BF02872710

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  • DOI: https://doi.org/10.1007/BF02872710

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