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Folia Microbiologica

, Volume 6, Issue 5, pp 299–305 | Cite as

The enhancing effect of homologous lymphoid cells on maturation of active antibody formation in newborn rabbits

  • M. Holub
Article
  • 14 Downloads

Summary

The transfer of large quantities (400 million) of living thymus or mesenteric lymph node cells stimulated and enhanced the active antibody response of newborn rabbits to the later administration of bacterial or protein antigen. Their enhancing effect was associated with stimulation of the organization of the mesenteric lymph nodes, with stimulation of differentiation of the plasma cells in these nodes and with an increase in lymphocytopoiesis in the spleen.

In the authors's view, this is due toa combination of the irritant effect of the homologous cells on the tissues of the recipient with the trophic effect of the disintegrating lymphocytes.

Keywords

Lymphoid Cell Correspond Lymph Node Adult Rabbit Thymus Cell Young Rabbit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Ускорение со зревания спосоъности к активному оъразованию антител у новорожденных кроликов гомологичными лимфоидными клетками

Abstract

Путем пересадки новорожденным крольчатам больших количеств (400 милл.) живых клеток зобной железы или брыжеечных узлов удавалось ускорить и повысить активную реакцию образования антител на вводимый позднее бактериальный или белковый антиген. Это усиливающее действие сопровождалось ускорением организации брыжеечных узлов из radix mesenterii и созревания плазматических клеток этих узлов и повышением лимфоцитопоэза в остальных лимфатических органах.

Мы полагаем, что речь идет о сочетании раздражающего действия гомологичных клеток на ткани реципиента и трофического действия в организме рецептора дезинтегрированных лимфоцитов.

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Copyright information

© Nakladatelství Československé akademie věd 1961

Authors and Affiliations

  • M. Holub
    • 1
  1. 1.Department of Microbiology, Institute of BiologyCzechoslovak Academy of SciencesPrague 6

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