Abstract
After irradiating a streptomyces isolated from soil with UV-light, a mutant was obtained which was no longer capable of chlorinating the tetracycline nucleus. The high amount of tetracycline produced (95% of the total activity of tetracycline compounds) was not influenced by the concentration of chloride ions in the medium. Taxonomic characterization indicates that the strain thus obtained designatedStreptomyces sp. 1717 (NCIB 9692), is different fromStreptomyces aureofaciens.
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Palečková, F., Řeháček, Z. & Hošťálek, Z. Biosynthesis of tetracycline. Folia Microbiol 13, 419–423 (1968). https://doi.org/10.1007/BF02869193
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DOI: https://doi.org/10.1007/BF02869193