Folia Microbiologica

, Volume 13, Issue 5, pp 419–423 | Cite as

Biosynthesis of tetracycline

Strain improvement and taxonomy of productive streptomyces
  • F. Palečková
  • Z. Řeháček
  • Z. Hošťálek


After irradiating a streptomyces isolated from soil with UV-light, a mutant was obtained which was no longer capable of chlorinating the tetracycline nucleus. The high amount of tetracycline produced (95% of the total activity of tetracycline compounds) was not influenced by the concentration of chloride ions in the medium. Taxonomic characterization indicates that the strain thus obtained designatedStreptomyces sp. 1717 (NCIB 9692), is different fromStreptomyces aureofaciens.


Streptomyces Tetracycline Strepto Aureomycin Oatmeal Agar 
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Copyright information

© Academia, nakladateletví Československé akademie věd 1968

Authors and Affiliations

  • F. Palečková
    • 1
  • Z. Řeháček
    • 1
  • Z. Hošťálek
    • 1
  1. 1.Research Institute of Antibiotics and BiotransformationsRoztoky near Prague

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