Folia Microbiologica

, Volume 13, Issue 2, pp 139–145 | Cite as

Steroid derivatives

IL. Formation of 5β-saturated steroid derivatives by the 11-hydroxylating fungusBeauveria globulifera
  • J. Protiva
  • V. Schwarz
  • J. Martínková


It was found in a study of the hydroxylating capacity of one of theFungi imperfecti, the genusBeauveria, some of the species of which are able to introduce the oxygen function into position 11α of various steroid compounds, that the enzyme activity ofBeauveria globulifera gives rise both to the corresponding 11α-hydroxy-derivative and to the 5β-saturated 11α-hydroxy-compound or a 5β-saturated 7β,11α-dihydroxy-compound. The isolation and the identification of the products of biotransformation of some steroids of the pregnane and androstane series byBeauveria globulifera is described.


Pregnane Beauveria Bassiana Steroid Compound Crude Mixture Biotransformation Reaction 
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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1968

Authors and Affiliations

  • J. Protiva
    • 1
  • V. Schwarz
    • 1
  • J. Martínková
    • 1
  1. 1.Research Institute of Pharmacy and BiochemistryPrague 9

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