Economic Botany

, Volume 31, Issue 3, pp 307–311 | Cite as

Cardiotonic glycosides from the latex of naucleopsis mello-barretoi, a dart-poison plant from North-West Brazil

  • Norman G. Bisset
  • Peter J. Hylands


Poison scraped from blowpipe darts made by the Makti Indians of the Upper Rio Uneiuxi, Rio Negro basin, and prepared from the latex of Naucleopsis mello-barretoi (Standl.) C. C. Berg, contained ca. 4.4% cardiotonic glycosides; one of the major glycosides present wasα-antiarin.

Latex fromN. mello-barretoi yielded ca. 1.3% of a complex mixture of cardiotonic glycosides; the major component was β-antiarin and it was accompanied by small amounts of α-antiarin, probably antioside, and unidentified glycosides.

The bark of the plant had only traces of cardiotonic glycosides; some components appeared to be the same as those in the latex, but the antiarins and antioside were absent.

Cardiotonic glycosides were not detected in the leaves.


MeOH Glycoside Bark EtOH Economic Botany 
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Copyright information

© The New York Botanical Garden 1977

Authors and Affiliations

  • Norman G. Bisset
    • 1
  • Peter J. Hylands
    • 1
  1. 1.Pharmacognosy Research Laboratories, Department of PharmacyChelsea College, University of LondonLondonEngland

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