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Indian Journal of Clinical Biochemistry

, Volume 16, Issue 2, pp 207–210 | Cite as

Evaluation of sevafilachek immunoassays and rapid ICT-filariasis test for detection of bancroftian filariasis

  • R. Alli
  • S. Kulkarni
  • M. V. R. Reddy
  • B. C. Harinath
Brief Communications

Abstract

A comparative analysis was made on the utility of SEVAFILACHEK-stick based immunoassays and commercially available ICT-filariasis test to detect active infection in different groups of bancroftian filariasis. The SEVAFILACHEK immunoassays were found to be useful to detect filarial infection in microfilaraemia and in a significant number of clinical filarial cases with acute, chronic and occult clinical manifestations. In the clinical cases, microfilariae are not usually detected in peripheral circulation. Employing SEVAFILACHEK assays 6 and 5 of the 7 samples of patients with chronic filarial disease, and 6 and 5 of 6 microfilaraemic cases gave positivity for filarial IgG antibodies and antigen respectively. Four of the 6 occult filarial samples were positive for antibodies and antigen. Filarial antigen was detected by ICT-filariasis test in blood samples of all the 6 microfilariaemic cases, 1 chronic filarial and 2 occult filarial samples. The main advantage of ICT assay is its rapid format and convenience for field use.

Key words

Bancroftian filariasis antigen antibody immunoassays rapid diagnostics 

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Copyright information

© Association of Clinical Biochemists of India 2001

Authors and Affiliations

  • R. Alli
    • 1
  • S. Kulkarni
    • 1
  • M. V. R. Reddy
    • 1
  • B. C. Harinath
    • 1
  1. 1.Department of Biochemistry & JB Tropical Disease Research CentreMGIMSSevagram(Wardha)India

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