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Indian Journal of Clinical Biochemistry

, Volume 16, Issue 2, pp 145–152 | Cite as

Cadmium, carcinogen, co-carcinogen and anti carcinogen

  • Ramesh Chandra
  • Sujata K. Dass
  • Priyanka Tomar
  • Manisha Tiwari
Reviews

Abstract

As a stress agent, inducing apoptosis and blocking it, Cd can have both helpful and harmful effects. The atmosphere is a thin envelope which makes the worid a global village. Cd is the most toxic metal in air. As both the first and second messenger of the stress response, it is synergistically toxic with all other stressors, including many other carcinogens. Elimination of Pb and its replacement with added benzene in gasoline appears to have increased the toxicity of atmospheric Cd. With scientific understanding of the molecular basis of Cd's role in carcinogenesis and anti-carcinogenesis, primary cancer prevention can be practiced by reducing Cd and chemical air pollution and educating the public on smoke cessation, healthy eating habits and stress reduction. Using the existing information on Cd and its effects, determinations could be made on established cancers so that individualized treatment protocols can be developed to improve patient care.

Keywords

Cadmium Carcinogen Co-carcinogen Anti-carcinogen 

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Copyright information

© Association of Clinical Biochemists of India 2001

Authors and Affiliations

  • Ramesh Chandra
    • 1
  • Sujata K. Dass
    • 1
  • Priyanka Tomar
    • 1
  • Manisha Tiwari
    • 1
  1. 1.Dr. B. R. Ambedkar Center for Biomedical ResearchUniversity of DelhiDelhi

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