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A general synthesis of thiazoles. Part 6. Synthesis of 2-amino-5-heterylthiazoles

  • S Rajappa
  • V Sudarsanam
  • V G Yadav
Organic
  • 31 Downloads

Abstract

2-Chloromethyl pyridine, 2-chloromethyl quinoline and 2-chloromethyl benzimidazole have been reacted with amidino thioureas to provide the corresponding 2-amino-5-(2-heteroaryl) thiazoles. 4-Chloromethyl thiazole failed to undergo this reaction.

Keywords

2-Amino-5-heteroarylthiazoles amidinothioureas 

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References

  1. Rajappa S and Sreenivasan R 1978Indian J. Chem. B16 749Google Scholar
  2. Rajappa S, Sudarsanam V, Advani B G and Rane A V 1982Proc. Indian Acad. Sci. (Chem. Sci.) 91 Google Scholar
  3. Ried W and Kaiser L 1976Liebigs Ann. Chem. 395Google Scholar

Copyright information

© the Indian Academy of Sciences 1982

Authors and Affiliations

  • S Rajappa
    • 1
  • V Sudarsanam
    • 2
  • V G Yadav
    • 1
  1. 1.CIBA-GEIGY Research CentreBombayIndia
  2. 2.The Boots Company (India) Ltd., SIONBombayIndia

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