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A general synthesis of thiazoles. Part 4. Synthesis of 5-acyl-2, 4-diaminothiazoles

  • S Rajappa
  • V Sudarsanam
  • V G Yadav
  • B V Gaikwad
Organic
  • 22 Downloads

Abstract

N,N,N′,N′-tetramethylguanidine has been added to methyl and phenyl isothiocyanates. Reaction of the adducts with α-haloketones has yielded 5-acyl-2-(substituted) amino-4-dimethylaminothiazoles.

Keywords

5-Acyl-2-amino-4-dimethylaminothiazoles 

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References

  1. Rajappa S and Advani B G 1970Indian J. Chem. 8 1145Google Scholar
  2. Rajappa S, Nair M D, Advani B G, Sreenivasan R and Desai J A 1979J. Chem. Soc. Perkin Trans. 1 1762CrossRefGoogle Scholar
  3. Rajasekharan K N and Sulekha A 1981Indian J. Chem. B20 549Google Scholar

Copyright information

© the Indian Academy of Sciences 1982

Authors and Affiliations

  • S Rajappa
    • 1
  • V Sudarsanam
    • 2
  • V G Yadav
    • 1
  • B V Gaikwad
    • 1
  1. 1.CIBA-GEIGY Research CentreBombayIndia
  2. 2.The Boots Company (India) Ltd., SIONBombayIndia

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