Pulmonary reperfusion injury : A comparison of bubble and membrane oxygenators
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Twenty cases of single valve replacement or atrial septal defect repair who underwent elective corrective surgery using either membrane (Capiox E) oxygenator (n=10) or bubble (Bentley 10™) oxygenator (n=10) were studied for the activation of cellular and humoral elements in blood. The bubble oxygenator was found to have more damaging effect of platelet sequestration and pulmonary sequestration of leucocytes. The C3c and’ c4 levels were found to be equally decreased in both groups. Both groups however showed no significant pneumocyte changes and there was no adverse effect on the postoperative clinical outcome in both groups.
KeywordsCardiopulmonary Bypass Complement Activation Atrial Septal Defect Lung Biopsy Pulmonary Sequestration
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