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Chinese Journal of Integrative Medicine

, Volume 12, Issue 1, pp 42–45 | Cite as

Thermodynamic study on antibacterial effect of different extracts from Radix Isatis

  • Zhao Yan-ling
  • Qu Fen
  • Xiao Xiao-he
  • Liao Qing-wen
  • Wang Jia-bo
  • Ma Yong-gang
  • Sun Yu-qi
Experimental Work and Research

Abstract

Objective: To study and analyze the antibacterial effects of different extracts from Radix Isatis.Methods: Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus, together with common pharmacological experiments.Results: The total extract, ethyl acetate (EtOAc) extract,n-butylalcohol (nBuOH) extract, chloroform (CHCl3) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl3 extract> total extract >P. E. extract.Conclusion: The antibacteriall effects of Radix Isatis were not limited to any active portion, showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.

Key words

Radix Isatis thermodynamics antibacterial effect 

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References

  1. 1.
    Zhou CP, Chen WS, Liu Y, et al. Biothermal analysis and biocalorimetry. Foundation China Sci 2000; (4): 201–204.Google Scholar
  2. 2.
    Yang Y, Liu Y, Zhu J, et al. Microcalorimetric study on the transcription start site mutagenesis. J Thermal Analysis Calorimetry 2004; 75(3): 293–300.CrossRefGoogle Scholar
  3. 3.
    Zhang JT. Experimental methods of modern pharmacology. Beijing: Union Publishing House of Beijing Medical University and Xiehe Medical University of China, 1998: 1413.Google Scholar
  4. 4.
    Monti M. Application of microcalorimetry to the study of living cells in the medical field. Thermochim Acta 1990; 172(5): 52–60.Google Scholar
  5. 5.
    Yan CG, Xie XY, Liu Y, et al. Survey of thermochemistry on characteristics of bacteria metabolism. Acta Hubei Agriculture Coll 1997; 17(3): 229–232.Google Scholar

Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press 2006

Authors and Affiliations

  • Zhao Yan-ling
    • 1
    • 2
  • Qu Fen
    • 3
  • Xiao Xiao-he
    • 1
  • Liao Qing-wen
    • 1
  • Wang Jia-bo
    • 1
  • Ma Yong-gang
    • 1
  • Sun Yu-qi
    • 1
  1. 1.Institute of Chinese Materia MedicaThe 302 Hospital of PLABeijing
  2. 2.Academy of Military Medical ScienceChina
  3. 3.Clinical Laboratorythe 302 Hospital of PLAChina

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