Abstract
Objective: To explore the clinical effect of therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder (GEFD).Methods: Retrospective analysis was carried out on 96 critical patients. They were 48 patients in the treated group treated with Dachengqi Decoction and 48 patients in the control group treated with Western medicine for promoting gastric dynamic force. The recovery rate, recovery time of gastro-enteric function, incidence rate and fatality rate of multiple organ dysfunction syndrome (MODS), as well as the level of plasma endotoxin (ET) before and after treatment between the two groups were compared.Results: Comparison between the two groups in gastro-enteric function recovery rate (81.3% vs 45.8%), functional disorder sustaining time in patients who got recovered (1.2±0.3 days vs 4.0±1.1 days), incidence rate (29. 17% vs 52.08%) and fatality rate (28.57% vs 56.00%) of MODS all showed significant difference (P< 0.05 orP< 0.01). The plasma level of ET after treatment in the treated group was significantly lower than that in the control group (P< 0. 05).Conclusion: Therapy of clearing hallow viscera has a good effect in treating critical patients with gastro-enteric function disorder, and could reduce the incidence and fatality of MODS.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Yang SL, Wang P, Li DB. Expermental study on the mechanism of protective effect of clearing the hollow fuorgans on the lung’s damage caused by partly ligating the large intestine. Chin J Integr Tradit West Med Dig 2003; 11(3): 154–156.
Li WF, Chen J, Yang XY, et al. Clinical observation on effect of rhubarb in treating patients with acute respiratory distress. Chin J Crit Care Med 2003; 23(2): 102.
Qin HB, Zhou SX. Modern therapy of multiple organ dysfunction syndrome. Beijing: People’s Military Medical Press, 2001: 20–29.
Hassoun HT, Kone BC, Mercer DW, et al. Postinjury multiple organ failure: the role of the gut. Shock 2001; 15: 1.
Moore FA. The role of the gastrointestinal tract in postinjury multiple organ failure. Am J Surg 1999; 178: 449–453.
Doig CJ, Sutherland LR, Sandham JD, et al. Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients. Am J Respir Crit Care Med 1998; 158: 444–451.
Chen DC, Jing BW, Yang XY, et al. Exploration on the mechanism of rhubarb in protecting intestinal membranous barrier. Chin Crit Care Med 1996; 8 (8): 449–451.
Wang KF, Lu FE, Xu LJ, et al. Comparative studies of therapeutic characteristics of three Chinese herbal preparations against febrile diseases on treating endotoxemic rabbits. J Microcirculation 2002; 12(4): 33–35.
Tian DH, editor. Practical Materia Medica. Beijng: People’s Medical Publishing House, 2002: 1333, 1375.
Liu F, Gao SJ, Hu HG, et al. Clinical study on treatment of shock induced gastro-enteric function disorder by rhubarb. Chin J Crit Care Med 2003; 23(1): 38–39.
Thijis LG, Hack CE. Time course of cytokine levels in sepsis. Intesive Care Med 1995; 21: 258–263.
Author information
Authors and Affiliations
Corresponding author
Additional information
Supported by the Fund of Hubei Administration of Health (No. 3-98)
Rights and permissions
About this article
Cite this article
Sheng-lan, Y., Dao-ben, L. Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder. Chin. J. Integr. Med. 12, 122–125 (2006). https://doi.org/10.1007/BF02857358
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02857358