Archives of Pharmacal Research

, Volume 7, Issue 1, pp 57–60 | Cite as

A sapogenin ofRandia siamensis

  • Won Sick Woo
  • Jae Sue Choi
  • Phichai Tovivich


From the roots ofRandia siamensis (Rubiaceae), 3β, 30-dihydroxy-urs-12-en-Z8-oic acid (30-hydroxy ursolic acid) was isolated and characterized by spectral data.


Randia siamensis Rubiaceae 30-hydroxyursolic acid 13C NMR 


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Literature Cited

  1. 1).
    Lapikanon, P., Tovivich, P., Woo, W.S. and Choi, J.S.: Phytochemical study onRandia siamensis.Arch. Pharm. Res. 6, 29 (1983).CrossRefGoogle Scholar
  2. 2).
    Budzikiewicz, H., Wilson, J. M. and Djerassi, C.: Mass spectrometry in structural and stereochemical problems. XXXII. Pentacyclic triterpenes.J. Am. Chem. Soc. 85, 3688 (1963).CrossRefGoogle Scholar
  3. 3).
    Cheung, H.T. and Yan, T.C., Constituents of Dipterocarpaceae resins. IV. Triterpenes ofShorea acuminata andS. resina-nigra.Aust. J. Chem. 25, 2003 (1972).Google Scholar
  4. 4).
    Seo, S., Tomita, Y. and Tori, K.: Carbon-13 NMR spectra of urs-12-enes and application to structural assignments of components ofIsodon japonicus tissue cultures.Tetrahedron Lett. 1975, 7.Google Scholar
  5. 5).
    Seo, S., Tomita, Y. and Tori, K.: Biosynthesis of ursene-type triterpenes from sodium [1,2-13C] acetate in tissue cultures ofIsodon japonicus Hara and re-assignments of13C nmr signals in urs-12-enes.JCS (Chem. Comm.)1975, 954.Google Scholar
  6. 6).
    Tori, K., Seo, S., Shimaoka, A. and Tomita, Y.: Carbon-13 NMR spectra of olean-12-enes. Full signal assignments including quaternary carbon signals assigned by use of indirect13C,1H spin couplings.Tetrahedron Lett. 1974, 4277.Google Scholar
  7. 7).
    Patt, S.L., and Shoolery, J.N.: Attached proton test for carbon-13 NMR.J. Mag. Res. 46, 535 (1982).Google Scholar
  8. 8).
    Talapatra, S.K., Sarkar, A.C. and Talapatra, B.: Two pentacylic triterpenes fromRubia cordifolia.Phytochemistry 20, 1923 (1981).CrossRefGoogle Scholar

Copyright information

© The Pharmaceutical Society of Korea 1984

Authors and Affiliations

  • Won Sick Woo
    • 2
  • Jae Sue Choi
    • 2
  • Phichai Tovivich
    • 1
  1. 1.Natural Products Research InstituteSeoul National UniversitySeoulKorea
  2. 2.Department of Chemistry, Faculty of SciencesChulalongkorn UniversityBangkokThailand

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