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Archives of Pharmacal Research

, Volume 7, Issue 1, pp 41–45 | Cite as

Effects of Red ginseng-crude saponin on plasma lipid levels in rats fed on a diet high in cholesterol and triglyceride

  • Chang Kiu Moon
  • Nae Young Kang
  • Yeo Pyo Yun
  • Soo Hwan Lee
  • Hyun Ah Lee
  • Tak Lim Kang
Original Articles

Abstract

The effect of Red ginseng saponin on plasma lipid levels in Wistar rats fed on a diet high in cholesterol and triglyceride was determined. A dose of Red ginseng-crude saponin (150 mg/kg/day) was administered orally for 4 weeks to Wistar rats fed on a diet containing 2% cholesterol and 10% olive oil. Plasma levels of total cholesterol, HDL-cholesterol and triglyceride were measured and lipoproteins were analyzed by using electrophoretic technique. Red ginseng saponin showed no significant changes of HDL-cholesterol level but it lowered plasma levels of total cholesterol and elevate those of triglyceride intensively.

Keywords

Red ginseng saponin Lipoprotein Hypocholesterolemic effect Hypertriglyceridemic effect DHL-cholesterol 

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Copyright information

© The Pharmaceutical Society of Korea 1984

Authors and Affiliations

  • Chang Kiu Moon
    • 1
  • Nae Young Kang
    • 1
  • Yeo Pyo Yun
    • 1
  • Soo Hwan Lee
    • 1
  • Hyun Ah Lee
    • 1
  • Tak Lim Kang
    • 2
  1. 1.College of PharmacySeoul National UniversitySeoul
  2. 2.Department of PharmacyDong-Duck Women’s CollegeSeoulKorea

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