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Effects of antitumor polysaccharides fromAlbizza julibrissin on immune function

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Abstract

Polysaccharide fractions were prepared fromAlbizzia julibrissin by different extraction schedules. The fractions obtained were designated as PS-I and PS-II, respectively. Further purification of PS-I by Sephadex G-200 column chromatography gave two subfractions, Alju A and Alju B. Each fraction showed marked antitumor activity against sarcoma 180 solid form but not ascite form. PS-I and PS-II increased delayed hypersensitivity in normal and tumor bearing mice. PS-I treatment led to moderate restoration of the suppressed antibody production in tumor bearing mice.

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Moon, C.K., Lee, B.G., Lee, S.H. et al. Effects of antitumor polysaccharides fromAlbizza julibrissin on immune function. Arch. Pharm. Res. 8, 277–282 (1985). https://doi.org/10.1007/BF02856504

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  • DOI: https://doi.org/10.1007/BF02856504

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