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Correlation betweenHelicobacter pylori infection and gastrointestinal symptoms in pregnancy

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Abstract

Nausea, vomiting, and other dyspeptic symptoms are common in pregnancy. This hospital-based, cross-sectional study was designed to determine the role ofHelicobacter pylori infection in gastrointestinal (GI) symptoms during pregnancy. Standardized verbal scales were used to evaluate the frequency and severity of GI symptoms in 54 women whose pregnancies were in the first 16 gestational weeks.H. pylori infection was defined as a positive serum immunoglobulin G result on an immunochromatographic assay. TheH. pylori seropositivity rate was higher in the pregnant women (69%) than in the general population (∼50%–55%), but seropositivity did not correlate with clinical symptoms. Moreover, no specific patterns of GI symptoms were uncovered in theH. pylori infected patients. Maternal age, body weight, parity, gestational week, and educational level were not associated withH. pylori infection; neither were the prevalence and severity of GI symptoms.

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Authors and Affiliations

  1. Section of Gastroenterology Department of Internal Medicine, Taichung Veterans General Hospital China Medical College, Taichung, Taiwan, R.O.C.

    Chun-Ying Wu M.D., M.P.H.

  2. Division of Maternal-Fetal Medicine Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.

    Jenn-Jhy Tseng M.D., Min-Min Chou M.D. & Sheng-Kai Lin M.D.

  3. Section of Gastroenterology Department of Internal Medicine, Taichung Veterans General Hospital, No. 160, Section 3, Taichung-Kang Road, 407, Taichung, Taiwan, R.O.C.

    Sek-Kwang Poon M.D. & Gran-Hum Chen M.D.

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  1. Chun-Ying Wu M.D., M.P.H.
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  2. Jenn-Jhy Tseng M.D.
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  3. Min-Min Chou M.D.
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  6. Gran-Hum Chen M.D.
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Wu, CY., Tseng, JJ., Chou, MM. et al. Correlation betweenHelicobacter pylori infection and gastrointestinal symptoms in pregnancy. Adv Therapy 17, 152–158 (2000). https://doi.org/10.1007/BF02853157

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