Advances in Therapy

, Volume 22, Issue 5, pp 419–423 | Cite as

The resistance ofEscherichia coli strains isolated from community-acquired urinary tract infections

  • Zeynep Sümer
  • Figen Coskunkan
  • Haluk Vahaboglu
  • Mehmet Bakir


Urinary tract infections (UTIs) are the most common infections caused byEscherichia coli. Most recent research demonstrates that antibiotic resistance has reached a critical point throughout the world, as increased use of antibiotics among nonhospitalized patients encourages the growth of drug-resistant pathogens among that population. The goal of this study was to determine the antimicrobial drug resistance ofE coli strains isolated from community-acquired UTIs in 5 different regions in Turkey. The minimum inhibitory concentrations of ciprofloxacin, gentamicin, sulfamethoxazole, trimethoprim, trimethoprim-sulfamethoxazole, and ampicillin and forE coli were determined with the agar dilution method. Among the 480 strains isolated, 8.3% were resistant to ciprofloxacin, 3.3% to gentamicin, 35.4% to sulfamethoxazole, 33.3% to trimethoprim, 27.9% to trimethoprim-sulfamethoxazole, and 40.8% to ampicillin. These results show that the antibiotics currently most effective againstE coli are ciprofloxacin and gentamicin. Local epidemiologic trends should be considered when prescribing antibacterial therapy. More research in bacterial gene mapping will be necessary to elucidate the influence of regional antimicrobial drug use and resistance in epidemiologic trends among the general population.


antimicrobial resistance Escherichia coli minimum inhibitory concentration urinary tract infections 


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Copyright information

© Health Communications Inc 2005

Authors and Affiliations

  • Zeynep Sümer
    • 1
  • Figen Coskunkan
    • 2
  • Haluk Vahaboglu
    • 2
  • Mehmet Bakir
    • 3
  1. 1.Department of MicrobiologyCumhuriyet UniversitySivasTurkey
  2. 2.Department of Infectious DiseasesKocaeli UniversityKocaeliTurkey
  3. 3.Department of Infectious DiseasesCumhuriyet UniversitySivasTurkey

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