Abstract
Due to changing characteristics of infective endocarditis in the past two decades, we, retrospectively analysed 28 cases of infective endocarditis in children of age less than 15 years at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar from December, 1983 to November, 1993.
The incidence of disease was observed as 1.5 cases/1000 children admitted with a M:F ratio of 2∶1. Three patients were of age less than 2 years (group I) as 25 were above 2 years of age (group II). The two groups had significant difference in portal of entry of infection, infective microorganisms, echocardiography and prognosis. Congenital heart disease was the commonest underlying cardiac lesion in 24 (85.71%) patients. Portal of entry of infection was apparent in 35.71% only; dental route being more frequent in group II. Streptococcus viridans (in 9 cases) followed by staphylococcus aureus (in 4 cases) were the two common organisms isolated.
Patients were treated, for a period of 4–6 weeks with a over all mortality rate of 25%. Factors associated with poor prognosis were age <2 years, staphylococcal infection ad negative blood cultures. Heart failure resistant to medical therapy was a leading cause of death.
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References
Bradenbarg RD, Glullani E, Wilson WR Geraci JE. Infective Endocarditis-A 25 years overview of diagnosis and therapy.J Amm Coll Cardiac 1983; 1:280.
Von Reyon CF, Levy BS, Arbeit RD, Friedland G, Crumpacker CS. Infective endocarditis: An analysis based on strict case definition.Ann Int Medicine 1981; 91 (Part-I) 505.
O'Brien JT, Geiser EA. Infective endocarditis and echocardiography.Am Heart J 1984; 108:386–394.
F Parrs, E Bouza, Jet al. Infective endocarditis in children.Paed Cardiology 1978; 11:77–81.
Watanakunakarn C. Infective endocarditis as a result of medical progress.Am J Med 1978; 64:917–919.
Johnson DH, Rosenthol A, Nada AS. A fourty year review of bacterial endocarditis in infancy and childhood.Circulation 1975; 51:581–588.
Schollin J, Bjarke B, Wesstrons G. Infective endocarditis in children.Acta Paediatr Scand 1985; 75:993–1005.
AJ Mansur, M Grinberg, G Bellotti, A Jatene, F Pileggi. Infective endocarditis in 1980: Experience at a heart hospital.Clin Cardiol 1990; 13:623–630.
Rajib choudhury, Anil Grover, Jagmohan Vermaet al. Active infective endocarditis observed in a Indian Hospital 1981–1991.Am J Cardial 1992; 70:1453–1458.
Jones HR, Seikerh RG, Seraci JE. Neurological manifestations of bacterial endocarditis.Ann of Int. medicine 1969; 71:21.
Bayliss R, Closke C, Okley CMet al. The microbiology and pathogenesis of infective endocarditis.Br. Heart Jr. 1983; 50:513.
I Weingerger, Z Rotenberg, D Zacharonitchet al. Native valve infective endocarditis in 1970's versas the 1980's under lying cardiac lesions and infecting organisms.Clinical Cardiology 1990; 13: 94.
Georg K, Dieter H, Axel H, Bennol Georg's. Increased risk of bacteril endocarditis in inflammtory bowel disese.The Amm. J. of Med. 1992; 91:391–395.
John Soo Kiam Mond. Infective endocarditis in chrons disease.Br Heart J 1989; 62:163–164.
Stanton BZ, Bathmore RS, Clemens JD, Canging repectrum of infective endocarditis in children. Analysis of 26 cases 1970–1979.Ann J Dis child 1984; 138: 720–725.
Van Hare FG, Ben Shachar G, Lichman Jet al. Infective endocarditis in infants and children during the past 10 years. A decade of change.Am Heart J 1984; 107: 1235–1240.
Romero J, Bouza E, Buzonlet al. Endocarditis on a Gove-Textube prosthesis.Pediatric Infec Dis J 1985: 296–298.
Johnson DT, Rosenthal A, Nados AS, Bcteril endocarditis in children under 2 years of age.Am J Dis child 1975; 129: 183–186.
Ravinovichs, Evans J Smith IM, Janury L. Longterm review of beterial endocarditis.Ann intern med 1965; 63:185–198.
Dillon T, Meyer RA, Korfhgen JCet al. Management of infective endocarditis using echocardiography. J. Ped. 1980; 86: 552–558.
Insidre V, J Alberto San, R, Victor R. Eustachian valve endocarditis.Br. Heart Journl 1990; 64:340–341.
Awadallah SM, Kavey RW, Byrum LJet al. The changing pattern of infective endocarditis in childhood.Am J Cardiol 1991; 68:90–94.
Skehan JD, Murray M, Mills PG. Infective endocarditis-incidence and mortality in noth east Thomas region.Br Heart J 1988; 59:62–68.
Andrew JB, Brenda P, Haytham J, Robert CT. The role of two dimensional echocardiography in the diagnosis of infective endocarditis.Angiology 1991; 552–560.
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Bhat, A.W., Jalal, S., John, V. et al. Infective endocarditis in infants and children. Indian J Pediatr 63, 204–209 (1996). https://doi.org/10.1007/BF02845245
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DOI: https://doi.org/10.1007/BF02845245