Brainstem auditory evoked response in tuberculous meningitis
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Brainstem auditory evoked response (BAER) abnormalities in tuberculous meningitis (TBM) were determined in 50 cases of tuberculous meningitis (36 male and 14 female) and 50 normal healthy children. Fifty six per cent cases had abnormal BAER findings. The commonest BAER abnormality observed in 32% was a combination of prolonged latency and prolonged interval while unilateral and bilateral absent response was observed in 4% cases. Prolonged latency was observed in 16% patients. Seizure activities, modified glasgow coma scale (GCS), raised intracranial pressure (ICP) and TBM stage III were significantly correlated with abnormal BAER, while age, sex, duration of illness, depressed sensorium, neurological deficit and CSF findings did not have a significant correlation with abnormal BAER. Follow up could be done in ten patients only. All the three patients with only prolonged latency had a normal BAER on follow up, two out of four patients with prolonged latency and prolonged interval had normalization of BAER while in three patients, initial as well as follow up BAER was normal. The present study shows that BAER abnormalities are observed in more than fifty per cent of the patients of tuberculous meningitis.
Key wordsBrainstem auditory evoked response Tuberculous meningitis Hearing impairment
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- 1.Lorber, J. Long term follow up of 100 children who recovered from tuberculous meningitis.Paediatric 1961; 28: 778.Google Scholar
- 3.Lyon MJ, Lyon ME. Early detection of hearing loss.Am J Public Health 1982; 73: 410–414.Google Scholar
- 4.Seth V. Diagnosis and treatment of tuberculosis. An Overview; tuberculosis in child (IAP).Publication of Indian Paediatrics, Official Journal of IAP, Ist edn. 1991, 8–52.Google Scholar
- 5.British Medical Research Council. Streptomycin in treatment of tuberculous meningitis. Report of the Committee on Streptomycin in tuberculosis trial.Lancet 1984; 1: 582–596.Google Scholar
- 6.Simon JE. Accidential injury and emergency. Medical services for children. In: Behrman RE (Ed),Nelson Textbook of paediatrics, 14th ed, W.B. Saunders Company, Pennsylvania 1992; 221.Google Scholar
- 7.Taylor MJ, Evoked potentials in paediatrics. In: Halliday AM (Ed),Evoked potentials in clinical testing 2nd edn; Churchill-Livingstone, London 1993; 489–521.Google Scholar
- 8.Swinscow TDV.Statistics at square one. British Medical Association. Tavistock square, London 4th ed. 1978.Google Scholar
- 14.Nagao S, Roccaforte and Moody R: Acute intracranial hypertension and auditory brainstem response—Part I.J. Neurosurg, 1979 A; 51: 661–676.Google Scholar
- 16.Hassler O: Arterial pattern of human brainstem, normal appearance and deformation in expanding supratentorial conditions.Neurology (Minncap) 1967; 17: 368–75.Google Scholar
- 19.Earnest Jawetz: Antimicrobial drugs.Lange's Basic and Clinical Pharmacology, Prentice-Hall Publishers, 5th ed., 647–648.Google Scholar