, Volume 6, Issue 10, pp 68–75 | Cite as

One hundred years of peptide chemistry

  • V. V. Suresh Babu
General Article


Emil Fischer is considered to be the founding father of the field of peptide chemistry and originator of the term peptide. In the beginning of the 20th century, Fischer had a clear vision to foresee the day when a protein would be synthesized. Subsequent to this brilliant beginning, progress however was slow for the next 50 years. In 1953, the chemical synthesis of oxytocin by duVigneaud was a landmark achievement. The subsequent decades witnessed the discovery of a vast number of biologically active peptides. The last two decades of the 20th century was filled with hopes of multiple simultaneous synthesis, peptide libraries and peptide vaccines. This article is a concise account of the types of family of peptides discovered and their biological role.


Oxytocin Nobel Prize Peptide Vaccine Peptide Antibiotic Peptide Chemistry 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Suggested Reading

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    E Schroder and K Lubke,The Peptides (in two volumes: Vol.1-Methods of peptide synthesis; Vol.2-Synthesis, occurrence and action of biologically active peptides), Academic Press, London, 1965.Google Scholar
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    M Bodanszky,Principles of Peptide Synthesis, Springer-Verlag, Berlin, 1984.Google Scholar
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    M Bodanszky,Peptide Chemistry: A Practical Textbook, Springer-Verlag, Berlin, 1988.Google Scholar
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    T Wieland and M Bodanszky,The World of Peptides: A Brief History of Peptide Chemistry, Springer-Verlag, Berlin, 1991.Google Scholar
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    J Jones,The Chemical Synthesis of Peptides, Clarendon Press, Oxford, 1991.Google Scholar
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    B Gutte,Peptides: Synthesis, Structures and Applications, Academic Press, San Diego, 1995.Google Scholar

Copyright information

© Indian Academy of Sciences 2001

Authors and Affiliations

  • V. V. Suresh Babu
    • 1
  1. 1.Department of Studies in ChemistryBangalore UniversityBangaloreIndia

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