Assessment of regional myocardial function in patients with hypertrophic cardiomyopathy by tissue strain imaging
- 21 Downloads
The value of tissue strain imaging (SI) in regional myocardial systolic and diastolic function assessment was studied. In 18 patients with nonobstructive hypertrophic cardiomyopathy (HCM) and 20 age-matched healthy subjects, regional myocardial longitudinal peak systolic strain in eject time (represented by εet) was measured at basal, mid and apical segments of septal, lateral and posterior walls of the left ventricle (LV) and compared between groups. εet had no significant difference between segments in control group (P>0.05), which displayed a decreasing trend from basal segments to apical ones, εet in the HCM group was significantly decreased (P<0.05) as compared with that in the healthy group. In the HCM group, εet in the midseptum was significantly less than at the basal and apical septum, and was also less than at the rest LV walls in the same group (P<0.01). The systolic reversed εet was noticed in 35% of the hypertrophic segments in HCM group. Significantly negative correlation existed between the absolute value of εet and wall thickness in the midseptum (r=−0.83). The post-systolic strain (PSS) segment number the and amplitudes in healthy group were significantly less than those in HCM group (P<0.05). Both regional myocardial systolic and diastolic functions were impaired in hypertrophic or non-hypertrophic segments in patients with the HCM, especially in hypertrophic segments. Strain imaging technique is a sensitive and accura tool in myocardial dysfunction assessment.
Key wordsechocardiography tissue strain imaging hypertrophic cardiomyopathy regional myocardial function
Unable to display preview. Download preview PDF.
- 3.Wang J J, Zheng L, Du Xet al. Echocardiography evaluation of myocardial strain rate of left ventricle and its influencing factors in healthy adults. Chin J Med Imaging Technol (Chinese), 2004, 20(10): 155–1557Google Scholar
- 7.Nagueh S F, Bachinski L L, Meyer Det al. Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy. Circulation, 2001, 104(2): 128–130PubMedGoogle Scholar