The Indian Journal of Pediatrics

, Volume 42, Issue 11, pp 326–328 | Cite as

Effects of dexamethasone on viscera and post natal development of neonatal rats

  • Kirt Kumar Jain

Summary and Conclusion

Neonatal albino rats injected with dexamethasone, sodium phosphate were studied at regular intervals by clinical, radiological and histological methods.

Growth of the soft and skeletal tissues of these animals was retarded, the skin was wrinkled and the appearance of the fur was delayed. The thymus was atrophied and the other internal organs were severely depleted of lymphocytes.

The effects are thought to be dose related and the drug action may occur at the cellular level, perhaps on nucleoproteins, which are responsible for the energy generating and division processes of the cells.


Dexamethasone Cortisone Antibody Produce Cell Estradiol Benzoate Cortisone Acetate 
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Copyright information

© Dr. K C Chaudhuri Foundation 1975

Authors and Affiliations

  • Kirt Kumar Jain
    • 1
  1. 1.Department of AnatomyMaulana Azad Medical College and Associated Irwin and G.B. Pant HospitalsNew Delhi-1

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