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Medical Oncology

, Volume 15, Issue 3, pp 199–201 | Cite as

Inversion of chromosome 16 in accelerated phase of chronic myeloid leukaemia: report of a case and review of the literature

  • M Čolović
  • G Janković
  • J Bila
  • V Djordjević
  • PH Wiernik
Paper

Abstract

A patient with a Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) developed a blast crisis (FAB subtype AML-M2) without a monocytic involvement. Karyotype showed the presence of inv(16)(p13;q22) in addition to Ph, in 16/20 marrow metaphases.

Keywords

chronic myeloid leukemia inv(16) 

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Copyright information

© Stockton Press 1998

Authors and Affiliations

  • M Čolović
    • 1
  • G Janković
    • 1
  • J Bila
    • 1
  • V Djordjević
    • 1
  • PH Wiernik
    • 2
  1. 1.Institute of HematologyUniversity Clinical CenterBelgradeYugoslavia
  2. 2.Albert Einstein Cancer Center and Department of OncologyMontefiore Medical CenterNew YorkUSA

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