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Antitumor activity of paclitaxel and epirubicin in human breast carcinoma, R-27

  • Immunology
  • 9th IWIDA International Workshop on Immunodeficient Animals Prague (Czech Republic) June 15–18, 1997
  • Published:
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Abstract

The antitumor effect of paclitaxel, epirubicin, and both in combination was tested using R-27, an estrogen receptor-positive human breast carcinoma. In anin vivo study using nude mice both drugs showed an additive effect, whereas they showed a supraadditive pattern inin vitro MTT assay. The combination of paclitaxel and epirubicin may enhance the antitumor effect on breast carcinoma.

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Authors and Affiliations

  1. Department of Surgery, Kitasato Institute Hospital, Tokyo, Japan

    F. Asanuma, Y. Yamada & E. Kawamura

  2. Department of Urology, Kitasato Institute Hospital, Tokyo, Japan

    K. Lee

  3. Department of Gynecology, Kitasato Institute Hospital, Tokyo, Japan

    H. Kobayashi

  4. Biomedical Laboratory, Kitasato Institute Hospital, Tokyo, Japan

    T. Yamada & T. Suzuki

  5. Department of Surgery, Keio University School of Medicine, Tokyo, Japan

    T. Kubota

Authors
  1. F. Asanuma
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  2. Y. Yamada
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  3. E. Kawamura
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  4. K. Lee
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  5. H. Kobayashi
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  6. T. Yamada
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  7. T. Suzuki
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  8. T. Kubota
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Asanuma, F., Yamada, Y., Kawamura, E. et al. Antitumor activity of paclitaxel and epirubicin in human breast carcinoma, R-27. Folia Microbiol 43, 473–474 (1998). https://doi.org/10.1007/BF02820793

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  • DOI: https://doi.org/10.1007/BF02820793

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