Folia Microbiologica

, Volume 47, Issue 3, pp 287–290 | Cite as

Efficacy of alkaloid (−)-corypalmine against spore germination of some fungi

  • S. Maurya
  • J. S. Srivastava
  • R. N. Jha
  • V. B. Pandey
  • U. P. Singh


Inhibition activity of the alkaloid (−)-corypalmine on spore germination of plant pathogenic and saprophytic fungi (Alternaria solani, A brassicicola, A. brassicae, A. melongenae, Curvularia pallescens, C. lunata, C. maculans, Curvularia sp.,Colletotrichum sp.,Helminthosporium speciferum, H. frumentacei, H. pennisetti, Heterosporium sp.,Penicillum sp.,Ustilago cynodontis) was determined. Spore germination of all the tested fungi was inhibited,Heterosporium sp. andUstilago cynodontis being the most sensitive (complete inhibition of spore germination was observed at the very low concentration of 200 ppm).Curvularia palliscens, C. maculans andCurvularia sp. were less sensitive; complete inhibition of spore germination occurred at 400 ppm.


Alkaloid Antifungal Activity Powdery Mildew Berberine Spore Germination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Ameer Basha S., Mishra R.K., Jha R.N., Pandey V.B., Singh U.P.: Effect of berberine and (±)-bicuculline isolated fromCorydalis chaerophylla on spore germination of some fungi.Folia Microbiol. 47, 161–165 (2002).Google Scholar
  2. Asthana A., Chandra H., Dikshit A., Dixit S.N.: Volatile fungitoxicants from leaves of some higher plants againstHelminthosporium oryzae.Z. Pflanzenkrankh. Pflanzensch. 89, 475–479 (1982).Google Scholar
  3. Atta-Ur-Rahman R., Nasreen A., Akhtar F., Shekhani M.S., Clardy J., Parvez M., Choudhary M.I.: Antifungal diterpenoid alkaloids fromDelphinium denudatum.J. Nat. Prod. 60, 474–475 (1997).Google Scholar
  4. Bracher F.: Polycyclic aromatic alkaloids. Ten annonaceous alkaloids with antimycotic activity.Arch. Pharm. Weincheim 327, 371–375 (1994).CrossRefGoogle Scholar
  5. Chakravorty D.K., Pariya S.N.: Inhibition of phytopathogenic fungi in some Indian medicinal plant extracts.Z. Pflanzenkrankh. Pflanzensch. 84, 221–233 (1977).Google Scholar
  6. Kobayashi K., Nishirio H., Fukushima M., Tomita H.: Antifungal activity of pisiferic acid and derivatives against rice blast fungus.Phytochemistry 26, 3175–3179 (1987).CrossRefGoogle Scholar
  7. Lyon G.P., Reglinski T., Newton A.C.: Novel disease control compounds: the potential to immunize plants against infection.Plant Pathol. 44, 407–427 (1995).CrossRefGoogle Scholar
  8. Mahajan V. M., Sharma A., Rattan A.: Antimycotic activity of berberin sulphate: an alkaloid from an Indian medicinal herb.Sabouraudia 20, 79–81 (1982).PubMedGoogle Scholar
  9. Maillard M., Gupta M.P., Hosteltmann K.: A new antifungal prenylated fluronone fromErythrina berteroana.Planta Med. 53, 563–564 (1987).PubMedCrossRefGoogle Scholar
  10. Maillard M., Hamberger M., Gupta M.P., Hosteltmann H.K.: An antifungal isoflavonone from a structural revision of a flavonone ofErythrina berteroana.Planta Med. 55, 281–282 (1989).PubMedCrossRefGoogle Scholar
  11. McCarthy P.J., Pitts T.P., Gunawardana G.P., Kelly Borges M., Pompani S.A.: Antifungal activity of meridine, a natural product from the marine spongeCorticium sp.J. Nat. Prod. 55, 1664–1668 (1992).PubMedCrossRefGoogle Scholar
  12. Preininger V., Novák J., Šimánek V., Šantavý F.: Isolation and chemistry of the alkaloids from plant of thePapaveraceae—LXXIII. Isolation and identification of alkaloids fromCorydalis lutea (L.)Dc.Planta Med. 33, 396–402 (1978).Google Scholar
  13. Prithiviraj B., Singh U.P.: Biological control of plant pathogens: a key to a serene agroecosystem.J. Res. ADU Appl. Sci. 10, 99–110 (1995).Google Scholar
  14. Prithiviraj B., Singh U.P., Khiste S., Ram D.: Effect of methanol extract ofAegle marmelos leaves onSclerotium rolfsii.Internat. J. Pharm. 34, 148–150 (1996).Google Scholar
  15. Prithiviraj B., Manickam M., Singh U.P., Ray A.B.: Antifungal activity of anacardic acid, a naturally occurring derivative of salicylic acid.Can. J. Bot. 74, 207–211 (1997a).Google Scholar
  16. Prithiviraj B., Singh U.P., Manicham M., Srivastava J.S., Ray A.B.: Antifungal activity of bergenin, a constituent ofFluggea microcarpa.Plant Pathol. 46, 244–248 (1997b).CrossRefGoogle Scholar
  17. Prithiviraj B., Singh U.P., Singh K.P., Schumacher K.P.: Field evaluation of ajoene, a constituent of garlic (Allium sativum) and neemazal, a product of neem (Azadirachta indica), against powdery mildew (Erysiphe pisi) of pea (Pisum sativum).Z. Pflanzenkrankh. Pflanzensch. 105, 274–278 (1998).Google Scholar
  18. Reimers F., Smolka S.E., Wemens S., Schumacher K.P., Wagner K.G.: Effect of ajoene, a compound derived fromAllium sativum, on phytopathogenic and epiphytic microorganisms.J. Plant Dis. Prot. 100, 622–633 (1993).Google Scholar
  19. Sarma B.K., Srivastava J.S., Prithiviraj B., Singh U.P., Pandey S.N.: Effect of Mannich bases on some plant pathogenic fungi.Folia Microbiol. 43, 393–398 (1998).Google Scholar
  20. Sarma B.K., Pandey V.B., Mishra G.D., Singh U.P.: Antifungal activity of berberine iodide, a constituent ofFumaria indica.Folia Microbiol. 44, 164–166 (1999).CrossRefGoogle Scholar
  21. Shamma M.:The Isoquinoline Alkaloids. Academic Press, New York-London 1972.Google Scholar
  22. Singh U.P., Pandey V.B., Singh K.P., Singh R.D.N.: Antifungal activity of some new flavonone and flavone glycosides ofEchinops echinatus.Can. J. Bot. 66, 1901–1903 (1988).Google Scholar
  23. Singh U.P., Pandey V.N., Wagner K.G., Singh K.P.: Antifungal activity of ajoene, a constituent of garlic (Allium sativum).Can. J. Bot. 68, 1354–1356 (1990).Google Scholar
  24. Singh U.P., Singh K.P., Tripathi V.K., Pandey V.B.: Antifungal activity of some naturally occurring plant alkaloids.Internat. J. Trop. Plant Dis. 12, 209–212 (1994).Google Scholar
  25. Singh U.P., Prithiviraj B., Wagner K.G., Schumacher K.P.: Effect of ajoene, a constituent of garlic (Allium sativum) on powdery mildew (Erysiphe pisi) of pea (Pisum sativum).J. Plant Dis. Prot. 102, 399–406 (1995).Google Scholar
  26. Singh S.K., Sarma B.K., Srivastava J.S., Singh U.P., Ray A.B.: Antifungal activity of Λ3-alstovenine, a plant alkaloid isolated fromAlstonia venenata.Folia Microbiol. 44, 510–512 (1999).CrossRefGoogle Scholar
  27. Singh U.P., Sarma B.K., Mishra P.K., Ray A.B.: Antifungal activity of venenatine, an indol alkaloid isolated fromAlstonia venenata.Folia Microbiol 45, 173–176 (2000).Google Scholar
  28. Singh B., Srivastava J.S., Khosa R.L., Singh U.P.: Individual and combined effects of berberine and santonin on spore germination of some fungi.Folia Microbiol. 46, 137–142 (2001).Google Scholar
  29. Srivastava B.P., Singh K.P., Singh U.P., Pandey V.B.: Effect of some naturally occurring alkaloids on conidial germination ofBotrytis cinerea.Bioved 5, 69–72 (1994).Google Scholar
  30. Volleková A., Košťálová D., Sochorová R.: Isoquinoline alkaloids fromMahonia aquifolium stem bark are active againstMalassezia spp.Folia Microbiol. 46, 107–112 (2001).CrossRefGoogle Scholar

Copyright information

© Folia Microbiologica 2002

Authors and Affiliations

  • S. Maurya
    • 1
  • J. S. Srivastava
    • 1
  • R. N. Jha
    • 2
  • V. B. Pandey
    • 2
  • U. P. Singh
    • 1
  1. 1.Department of Mycology and Plant Pathology, Institute of Agriculture SciencesBanaras Hindu UniversityVaranasiIndia
  2. 2.Department of Medicinal Chemistry, Institute of Medical SciencesBanaras Hindu UniversityVaranasiIndia

Personalised recommendations