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Folia Microbiologica

, Volume 40, Issue 4, pp 436–440 | Cite as

Characterization of the limited specificity of antigen recognition in earthworms

  • M. Bilej
  • L. Tučková
  • A. Romanovský
Reviews and Papers

Abstract

Earthworms respond to parenteral stimulation with a protein antigen by the formation of an antigen-binding protein. Earthworms were parenterally stimulated with different proteins and the protein binding was estimatedin vitro on both humoral and cellular levels. The binding was significantly higher when the same protein was used forin vivo stimulation. The degree of specificity of the antigen-binding protein after the secondaryin vivo challenge increased, but even so it was considerably lower than that of vertebrate immunoglobulins.

Keywords

Human Serum Albumin Protein Antigen Coelomic Fluid Coelomic Cavity Parenteral Stimulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ABP

antigen-binding protein

LBSS

Lumbricus balanced salt solution

ARS-HSA

arsanylated human serum albumin

BSA

bovine serum albumin

LPS

lipopolysaccharide

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References

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Copyright information

© Folia Microbiologica 1995

Authors and Affiliations

  • M. Bilej
    • 1
  • L. Tučková
    • 1
  • A. Romanovský
    • 2
  1. 1.Department of Immunology and Gnotobiology Institute of MicrobiologyAcademy of Sciences of the Czech RepublicPrague 4Czech Republic
  2. 2.Faculty of ScienceCharles University PraguePrague 2Czech Republic

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