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Gastroenterologia Japonica

, Volume 26, Issue 2, pp 157–161 | Cite as

Prevalence of chronic liver diseases and anti-HCV antibodies in different districts of Saga, Japan

  • Yoichi Setoguchi
  • Kyosuke Yamamoto
  • Iwata Ozaki
  • Nobuaki Fujio
  • Toshitsugu Kariya
  • Takahiro Sakai
  • Sadato Fujii
Liver, Pancreas, and Billiary Tract

Summary

The authors examined the contribution of Hepatitis C Virus (HCV) to the morbidity of chronic liver diseases (CLD) in selected districts of Saga, Japan, one group with low (L) and the other with a high (H) mortality rate of CLD. Age and sex-matched epidemiological studies showed an extremely high morbidity of CLD in the H-districts (5.3%) and a low one in the L-districts (2.1%). Randomized selected studies of anti-HCV antibodies showed an extremely high frequency of 10.8% in the H-district and a frequency of 4.6% in the L-district. In addition, the number of subjects with both CLD and positive anti-HCV antibodies was significantly higher in subjects older than the fifth decade, in the H-district. The high prevalence of HCV may be related to the high morbidity and mortality rate of CLD in these districts of Japan.

Key words

chronic liver disease epidemiology hepatitis C virus 

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Copyright information

© The Japanese Society of Gastroenterology 1991

Authors and Affiliations

  • Yoichi Setoguchi
    • 1
  • Kyosuke Yamamoto
    • 1
  • Iwata Ozaki
    • 1
  • Nobuaki Fujio
    • 1
  • Toshitsugu Kariya
    • 1
  • Takahiro Sakai
    • 1
  • Sadato Fujii
    • 2
  1. 1.Department of Internal MedicineSaga Medical SchoolSagaJapan
  2. 2.Fukuoka Health CenterFukuokaJapan

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