CardioVascular and Interventional Radiology

, Volume 18, Issue 2, pp 135–136 | Cite as

Re: Histological analysis of atherectomy specimens: an opportunity neglected to guide therapy preventing restenosis

  • Xiaoming Yang
  • Hannu Manninen
  • Seppo Solmakallio
Letter to the Editor


Intimal Hyperplasia Nonmuscle Myosin Saphenous Vein Bypass Coronary Smooth Muscle Coronary Restenosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Waller BF, Johnson DE, Schnitt SJ, Pinkerton CA, Simpson JB, Baira DS (1993) Histologic analysis of directional coronary atherectomy samples: A review of findings and their clinical relevance. Am J Cardiol 72:80E-87EPubMedCrossRefGoogle Scholar
  2. 2.
    Höfling B, Welsch U. Heimerl J, Gonchior P, Bauredel G (1993) Analysis of atherectomy specimens. Am J Cardiol72:96E-107EPubMedCrossRefGoogle Scholar
  3. 3.
    Miller MJ, Kuntz RE,-Friedrich SP, Leidig GA, Fishman RF, Schnitt SJ, Bairn DS, Safian RD (1993) Frequency and consequences of intimai hyperplasia in specimens retrieved by directional atherectomy of native primary coronary artery stenoses and subsequent restenoses. Am J Cardiol 71:652–658PubMedCrossRefGoogle Scholar
  4. 4.
    Brien ER, Alpers CE, Stewart DK, Ferguson M, Tran N, Gordon D, Benditt EP, Hinohara T, Simpson JB, Schwartz SM (1993) Proliferation in primary and restenotic coronary atherectomy tissue: Implications for antiproliferative therapy. Circ Res 73:223–231Google Scholar
  5. 5.
    Garratt KN, Edwards WD, Kaufmann UP, Vlietstra RE, Holmes DR Jr (1991) Differential histopathology of primary atherosclerotic and restenotic lesions in coronary arteries and saphenous vein bypass grafts: Analysis of tissue obtained from 73 patients by directional atherectomy. J Am Coll Cardiol 17:442–448PubMedCrossRefGoogle Scholar
  6. 6.
    Bauriedel G, Windsterter U, Demaio SJ Jr, Kandolf R, Hofling B (1992) Migratory activity of human smooth muscle cells cultivated from coronary and peripheral primary and restenotic lesions removed by percutaneous atherectomy. Circulation 85: 554–564PubMedGoogle Scholar
  7. 7.
    Simons M, Ledere G, Safian RD Isner JM, Weir L, Baim DS (1993) Relation between activated smooth-muscle cells in coronary-artery lesions and restenosis after atherectomy. N Engl J Med328:608–613PubMedCrossRefGoogle Scholar
  8. 8.
    Schnitt SJ, Safian RD, Kuntz RE, Schmidt DA, Bairn DS (1992) Histologie findings in specimens obtained by percutaneous directional coronary atherectomy. Hum Pathol23:415–420PubMedCrossRefGoogle Scholar
  9. 9.
    Grant MB, Wargovich TJ, Ellis EA, Caballero S, Mansour M, Pepine CJ (1994) Localization of insulin-like growth factor I and inhibition of coronary smooth muscle cell growth by somatostatin analogues in human coronary smooth muscle cells: A potential treatment for restenosis? Circulation 89:1511–1517PubMedGoogle Scholar
  10. 10.
    Voisard R, Seitzer U, Baur R, Dartsch PC, Osterhues H, Hoher M, Hombach V (1994) Corticosteroid agents inhibit proliferation of smooth muscle cells from human atherosclerotic arteries in vitro. Int J Cardiol 43:257–267PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York Inc 1995

Authors and Affiliations

  • Xiaoming Yang
    • 1
  • Hannu Manninen
    • 1
  • Seppo Solmakallio
    • 1
  1. 1.Department of Clinical Radiology KuopioUniversity Hospital KuopioFinland

Personalised recommendations