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The Indian Journal of Pediatrics

, Volume 52, Issue 4, pp 395–400 | Cite as

Ventriculitis complicating pyogenic meningitis in neonates

  • Nisar A. Mir
Original Articles

Abstract

Ventriculitis, was diagnosed in 17 cases of neonatal bacterial meningitis by positive culture and/or leucocytosis of ventricular fluid. Majority of the patients were female (14) and 13 were preterm. Maternal and/or obstetric complications were present in 82 per cent. Mean age of diagnosis of meningitis was 7·7±5·1 days. In all patients blood and CSF cultures were identical: E. coli (11), group B streptococcus (3), citrobacter-enterobacter (2) and pseudomonas (1). Six received systemic therapy and 11 were administered combined systemic and intraventricular therapy. Overall mortality rate was 23·5 per cent and eight of the 13 survivors were abnormal on follow up. Outcome was related to the duration to render the CSF sterile and to the interval between the diagnosis of meningitis and ventriculitis. The mortality was significantly lower in patients treated with combined systemic and intraventricular therapy.

Key words

Neonatal meningitis ventriculitis intraventricular therapy 

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Copyright information

© Dr. K C Chaudhuri Foundation 1985

Authors and Affiliations

  • Nisar A. Mir
    • 1
  1. 1.Division of Perinatology, Department of PediatricsHospital for Sick ChildrenTorontoCanada

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