Skip to main content
Log in

A simple model of growth and product formation in cell suspensions ofCatharanthus roseus G. Don

  • Original Articles
  • Published:
Applied Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

This paper describes the application of a simple log-linear model to suspension cultures of the species Catharanthus roseus G. Don. Data obtained experimentally have been interpolated by a cubic spline to give data points of regular time period. A logarithmic transformation has been applied and a linear model fitted to these transformed variables. The results show that there is a reasonable fit to the experimental data cited.

Using this model a one-step ahead prediction is made for a series of untried experimental variables, and the results generated are compared with the experimental data subsequently obtained.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Fowler, M. W. (1982),Biochem. Soc. Trans. 11, 23.

    Google Scholar 

  2. Smart, N. J. (1984),Lab. Practice 33, 1, 11–36.

    CAS  Google Scholar 

  3. Staba E.J., ed. (1980),Plant Tissue Culture as a Source of Biochemicals, Boca Raton, Florida, CRC Press.

    Google Scholar 

  4. Morris, P., and Fowler, M. W. (1980),Biochem. Soc. Trans. 8, 638.

    Google Scholar 

  5. Zenk, M. H., El-Shagi, H.,Arens, H., Stockigt, H., Weiler, E. W., and Deus, B. (1978), inPlant Cell Culture and Its Biotechnological Application, Barz, W., Reinhard, E., and Zenk, M. H. (eds.), Springer-Verlag, Berlin, pp. 27–43.

    Google Scholar 

  6. Street, H. E. (1973),Plant Tissue and Cell Culture, Blackwells Botanical Monographs, Oxford.

    Google Scholar 

  7. Pareilleux, A., and Chaubet, N. (1980),Biotechnol. Lett. 2 (6), 291.

    Article  Google Scholar 

  8. Contois, D. E. (1959),J. Gen. Microbiol. 21, 40.

    CAS  Google Scholar 

  9. Aiba, S., Shoda, M., and Nagatani, M. (1968),Biotechnol. Bioeng. 10, 845.

    Article  CAS  Google Scholar 

  10. Murashige, T., and Skoog, F. (1962),Physiol. Plant 15, 473.

    Article  CAS  Google Scholar 

  11. Fowler, M. W. (1983), inPlant Biotechnology, Mantell, S. H., and Smith, H., eds., Society for Experimental Biology Seminar Series and Cambridge University Press, Cambridge, pp. 3–37.

    Google Scholar 

  12. Wilson, S. B., King, P., and Street, H. E. (1971),J. Exp. Bot. 21, 177.

    Article  Google Scholar 

  13. Handel, E. van. (1968),Anal. Biochem. 22, 280.

    Article  Google Scholar 

  14. Karim, M. N., Mureira, A. R., and Grogen, A. (1982), Modelling and Actaptive Control of a Fermentation System, inProceedings of the 1982 American Control Conference, vol.3. pp. 925–930.

    Google Scholar 

  15. Cox, M. G. (1975),J. Inst. Math. Appl. 15, 95.

    Article  Google Scholar 

  16. Strejc, V. (1980),Automatica 16, 535.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bailey, C., Nicholson, H., Morris, P. et al. A simple model of growth and product formation in cell suspensions ofCatharanthus roseus G. Don. Appl Biochem Biotechnol 11, 207–219 (1985). https://doi.org/10.1007/BF02798477

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02798477

Index Entries

Navigation