Response of hepatic metallothionein to iron administration
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Female broiler chicks receiving an ip injection of Fe (10 mg/kg bw) were found to have a greatly increased level of hepatic metallothionein. The increase in metallothionein was not correlated with changes in serum corticosterone. Attempts to vary serum corticosterone levels by feeding metyrapone, an 11-β steroid hydroxylase inhibitor, were unsuccessful.
Index EntriesIron corticosterone metallothionein metyrapone
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- 4.C. McCormack,Proc. soc. Exp. Biol. and Med. 176, 392 (1984).Google Scholar
- 9.J. A. Thomas, and M. G. Mawhinney,Synopsis of Endocrine Pharmacology, Univ. Park Press, Baltimore, MD, 1973.Google Scholar
- 11.H. S. Siegel, N. R. Gould, and J. W. Latimer,Proc. Soc. Exp. Biol. and Med. 178, 523 (1985).Google Scholar
- 13.A. B. Myles, and J. R. Daley,Corticosterone and ACTH Treatment. Principles and Problems, Edward Arnold, London, 1974.Google Scholar
- 14.L. E. Edqvist, and E. D. B. Johansson, “Radioimmunoassay and Competitive Binding Protein for Measurement of Certain Steroid Hormones in Farm animals,” inIsotope Studies on the Physiology of domestic Animals (Athens, Greece International Atomic Energy Agency, Vienna, 1972), pp. 245–258.Google Scholar
- 16.C. McCormack,Fed. Proc. 44, 1853 (1985).Google Scholar