Influence of interfacial adsorption on the system constants of the solvation parameter model in gas-liquid chromatography
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The influence of interfacial adsorption as a retention mechanism on the system constants of the solvation parameter model for the polar stationary phase poly(diethylene glycol succinate) was studied as a function of phase loading and temperature. The solvation parameter model provides reasonable models for sorption conditions (mixed retention) that are chemically sensible and only slightly less statistically sound that the partition models. Interfacial adsorption leads to a linear change in the system constants that can be predicted as a function of phase loading (volume) for high phase loadings (> 8%w/w) at a constant temperature. The changes in the system constants with temperature show the same trends for the sorption and partition models but with different slopes. As a unifying framework it is suggested that the retention properties of the interfacial region resemble those of the bulk solvent except that the interfacial region is less cohesive and the intensity of polar interactions are reduced. The impact of interfacial adsorption on the interpretation of stationary phase solvation properties, the estimation of retention for computer-aided method development, and the estimation of solute descriptors using the solvation parameter model is indicated.
Key WordsGas chromatography Solvation parameter model Interfacial adsorption effects System constants
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