Biological Trace Element Research

, Volume 65, Issue 3, pp 197–210 | Cite as

Mercury-binding capacity of organic and inorganic selenium in rat blood and liver

  • Kari Seppänen
  • Reino Laatikainen
  • Jukka T. Salonem
  • Marjatta Kantola
  • Simo Lötjönen
  • Mikko Harri
  • Llisa Nüurminen
  • Jari Kaikkomem
  • Kristiima Nyyssönen
Original Articles


The mercury-binding capacity of seleno-DL-methionine and selenium dioxide was assessed in male Wistar rats. Mercury was supplied as fish loaves made of northern pike or rainbow trout. We used a selenium concentration of 3.4 mg/kg fish, about sixfold compared to the equivalent quantity of mercury. Seleno-DL-methionine had a tendency to increase both methyl mercury and total mercury in blood, although it also seemed to reduce the proportion of methyl mercury of total mercury. Selenium dioxide lowered mercury levels by 24–29% both in the blood and in the liver of rats that were fed with northern pike.

Index Entries

Mercury methyl mercury organic selenium inorganic selenium mercury-binding capacity lipid peroxidation response index 


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Copyright information

© Humana Press Inc 1998

Authors and Affiliations

  • Kari Seppänen
    • 1
  • Reino Laatikainen
    • 1
  • Jukka T. Salonem
    • 2
  • Marjatta Kantola
    • 1
  • Simo Lötjönen
    • 1
  • Mikko Harri
    • 3
  • Llisa Nüurminen
    • 3
  • Jari Kaikkomem
    • 2
  • Kristiima Nyyssönen
    • 2
  1. 1.Department of ChemistryUniversity of KuopioKuopioFinland
  2. 2.Research Institute of Public HealthUniversity of KuopioKuopioFinland
  3. 3.Department of Applied Zoology and Veterinary MedicineUniversity of KuopioKuopioFinland

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