Cell Biophysics

, Volume 1, Issue 4, pp 309–329 | Cite as

Effective coupling of four independent membrane systems in steady-state oxidative phosphorylation

  • Terrell L. Hill


Alexandre et al. have proposed a four-system model of oxidative phosphorylation. The thermodynamic consequences of this model are explored, assuming as a first approximation that these four systems can be treated as a self-contained group. The method can be generalized, in higher approximations, to include further systems and other complications. Respiratory control is considered from the point of view of the model. Self-consistent numerical examples are given to represent mitochondrial activity in state 3 and in state 4.

Key Words

Oxidative phosphorylation, steady state oxidative phosphorylation, four-system model proton transport, in oxidative phosphorylation respiratory control thermodynamics, of oxidative phosphorylation kinetics, of oxidative phosphorylation 


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Copyright information

© The Humana Press Inc 1979

Authors and Affiliations

  • Terrell L. Hill
    • 1
  1. 1.Laboratory of Molecular Biology, National Institute of Arthritis, Metabolism, and Digestive DiseasesNational Institutes of HealthBethesda

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