Dietary iron loading does not influence biliary iron excretion in rats
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The effect of dietary iron loading on biliary iron excretion was investigated with male Wistar rats aged 6 wk. The rats were fed purified diets with either 174 or 1740 mg FeSO4. 7H2O/kg diet and demineralized water for 6 wk. Blood haemoglobin, hematocrit, and iron concentrations in kidney and heart were not affected and iron concentrations in liver, spleen, and tibia were significantly raised after feeding the high-iron diet. The high-iron diet did not raise biliary iron excretion, suggesting that biliary iron excretion does not play an important role in regulating iron metabolism in rat after dietary iron loading.
Index EntriesBile iron status rat
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- 1.E. J. Underwood,Trace Elements in Human and Animal Nutrition, Academic Press, New York, p. 13, (1977).Google Scholar