Biological Trace Element Research

, Volume 51, Issue 2, pp 169–176 | Cite as

A spectroscopic study of the interaction of the VO2+ cation with the two components of chondroitin sulfate

  • Susana B. Etcheverry
  • Patricia A. M. Williams
  • Enrique J. Baran


The interaction of the vanadyl (IV) cation with N-acetyl-D-galactosamine, D-galactosamine, and D-glucuronic acid has been investigated by electron absorption spectroscopy at different mental to ligand ratios and pH values. In the case of D-glucuronic acid, a more detailed study was undertaken, using differential IR spectroscopy in solution. The results show that the cation interacts with the two nitrogenated molecules only at higher pH values, generating 2∶1 lig-and to metal complexes in which coordination occurs through two pairs of deprotonated OH groups of the rings. In the case of D-glucuronic acid, the IR-measurements allowed a wider insight into the structural characteristics of the complexes generated in acidic media. The involvement of the glycosidic oxygen atom in coordination, is suggested at pH=3.

Index Entries

VO2+/N-acetyl-D-galactosamine VO2+/D-galactosamine VO2+/D-glucuronic acid interactions infrared and electronic spectra coordination properties 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    S. B. Etcheverry, P. A. M. Williams, and E. J. Baran,Biol. Trace Element Res. 42, 43. (1994).CrossRefGoogle Scholar
  2. 2.
    F. S. Parker,Applications of Infrared Spectroscopy in Biochemistry, Biology and Medicine, Adam Hilger London, 1971.Google Scholar
  3. 3.
    F. S. Parker,Applications of Infrared, Raman and Resonance Raman Spectroscopy in Biochemistry, Plenum, New York, 1983.Google Scholar
  4. 4.
    G. Urretavizcaya and E. J. BaranZ. Naturforsch. 42b, 1537 (1987).Google Scholar
  5. 5.
    P. A. M. Williams and E. J. Baran,J. Inorg. Biochem. 50, 101 (1993).CrossRefGoogle Scholar
  6. 6.
    M. Branca, A. Dessi, and D. Sanna,J. Inorg. Biochem. 45, 169 (1992).PubMedCrossRefGoogle Scholar
  7. 7.
    E. J. Baran, inMetal Ions in Biological Systems, Vol. 31, 129 H. Sigel and A. Sigel, eds., Marcel Dekker, New York, 1995.Google Scholar
  8. 8.
    K. A. Connors,Binding Constants, Wiley, New York, 1981.Google Scholar
  9. 9.
    G. Micera, A. Dessi, H. Kozlowski, B. Radomska, J. Urbanska, P. Decock, B. Dubois, and J. Olivier,Carbohydr. Res. 188, 25 (1989).CrossRefGoogle Scholar
  10. 10.
    M. Branca, G. Micera, D. Sanna, A. Dessi, and H. Kozlowski,J. Chem. Soc. Dalton Transact. 1990, 1997.Google Scholar
  11. 11.
    K. Nakamoto,Infrared and Raman Spectra of Inorganic and Coordination Compounds, 3rd. Ed., Wiley, New York, 1978.Google Scholar
  12. 12.
    D. Lin-Vien, N. B. Colthup, W. G. Fateley, and J. G. Grasselli,The Handbook of Intrared and Raman Characteristic Frequencies of Organic Molecules, Academic, Boston, 1991.Google Scholar
  13. 13.
    K. Nakanishi,Infrared Absorption Spectroscopy, Practical, Nankodo, Tokyo, 1962.Google Scholar
  14. 14.
    C. G. Barraclough, D. C. Bradley, J. Lewis, and I. H. Thomas,J. Chem. Soc. 1961, 2601.Google Scholar

Copyright information

© Humana Press Inc. 1996

Authors and Affiliations

  • Susana B. Etcheverry
    • 1
  • Patricia A. M. Williams
    • 1
  • Enrique J. Baran
    • 1
  1. 1.Química Inorgánica (QUINOR), Facultad de Ciencias ExactasUniversidad Nacional de La PlataLa PlataArgentina

Personalised recommendations