International Journal of Pancreatology

, Volume 18, Issue 3, pp 277–283 | Cite as

Inflammatory pseudotumor of the pancreas

  • Steven H. Kroft
  • Steven J. Stryker
  • Jane N. Winter
  • Gulchi Ergun
  • M. Sambasiva Rao
Case Report


We describe a rare example of inflammatory pseudotumor of the pancreas in a 42-yr-old woman, which developed following chemotherapy for lymphoma of the uterine cervix. The patient had developed fatigue, weight loss abdominal pain, and anemia; abdominal CT scan showed a large mass in the pancreas. Examination of the resected specimen revealed a fleshy, well-circumscribed, 7-cm mass., Histologically, there was a hypocellular to moderately hypercellular, bland spindle-cell proliferation admixed with a prominent infiltrate of lymphocytes, histiocytes, and plasma cells. The spindle cells were vimentin positive but negative for muscle markers; electron microscopy revealed only fibroblastic cells. DNA analysis revealed a diploid population with low S-phase fraction. The patient was well at 6-mo follow-up. It is important for the pathologist to be aware of the existence of this entity in unusual locations such as the pancreas so as to avoid a mistaken diagnosis of malignancy.

Key Words

Pancreas pseudotumor inflammatory 


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Copyright information

© Humana Press Inc 1995

Authors and Affiliations

  • Steven H. Kroft
    • 1
  • Steven J. Stryker
    • 2
  • Jane N. Winter
    • 2
  • Gulchi Ergun
    • 3
  • M. Sambasiva Rao
    • 1
  1. 1.Department of PathologyNorthwestern University Medical SchoolChicago
  2. 2.Department of SurgeryNorthwestern University Medical SchoolChicago
  3. 3.Department of MedicineNorthwestern University Medical SchoolChicago

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