Biological Trace Element Research

, Volume 34, Issue 3, pp 279–286 | Cite as

Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells

  • Haimanti Dhir
  • Archana Sharma
  • Geeta Talukder


Essential trace elements such as iron (Fe) are known to interact with nonessential metals like lead (Pb), influencing its metabolism. Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino miceMus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration.

Index Entries

Lead iron interaction chromosomal aberrations 


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Copyright information

© The Humana Press, Inc 1992

Authors and Affiliations

  • Haimanti Dhir
    • 1
    • 2
  • Archana Sharma
    • 1
    • 2
  • Geeta Talukder
    • 1
    • 2
  1. 1.Centre of Advanced Study in Cell and Chromosome Research, Department of BotanyUniversity of CalcuttaCalcutta
  2. 2.Vivekananda Institute of Medical SciencesCalcuttaIndia

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