Gastroenterologia Japonica

, Volume 25, Issue 4, pp 411–416 | Cite as

Endoscopic treatment for submucosal tumors of the esophagus: Studies in 25 patients

  • Yoshiki Eda
  • Shigeru Asaki
  • Lin Yamagata
  • Shuichi Ohara
  • Daisuke Shibuya
  • Takayoshi Toyota
Alimentary Tract


Twenty-five patients with submucosal tumor of the esophagus were treated endoscopically. All patients underwent submucosography. The tumors were classified as intra-luminal or intra-mural types according to growth pattern. Twenty tumors were resected using electrocautery in single sessions. Another 5 lesions (more than 20mm in diameter) were subjected to absolute ethanol injections in multiple sessions to necrotize the tissue, after the overlying mucosa was stripped off by electrocautery. These procedures were not accompanied with serious complications such as perforation or massive bleeding. Oozing bleeding occurred in 3 patients, which was easily stopped by topical injection of absolute ethanol with an endoscope. Esophageal stenosis did not occur. Local reccurence of a submucosal tumor was found in a patient after 14 months, and was retreated successfully. Although the wall of the esophagus is thinner than that of the stomach, endoscopic treatment for a submucosal tumor of the esophagus can be performed safely. Submucosography and endoscopie ultrasonography reveals the extent of the tumor in relation to the esophageal wall thickness. These examinations are helpful in preventing complications. Endoscopie treatment for submucosal tumors using electrocautery and topical injection of absolute ethanol were effective and safe.

Key words

endoscopic treatment esophagus submucosal tumor 


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  1. 1.
    Classen M, Ruppin H, Koch H, et al: Struktur, Heilungstendenz und Rezidive nach endoscopischen Polypektomien im oberen Verdauungstrakt. In: Endoskopische Polypektomie im Gastrointestinaltract, Symposium in Erlangen im Marz, Georg Thieme Verlag Stuttgart 1973;33–39Google Scholar
  2. 2.
    Asaki S, Watanabe S, Iwabuchi J, et al: Report on gastric submucosal tumor and sarcoma (including submucosal tumor like lesions)- From the questionnaire of 15 institutions in Tohoku regions-Gastroenterol Endosc 1975;17:262–275 (in Japanese)Google Scholar
  3. 3.
    Kuramata H, Etoh S, Miyamoto S: On the endoscopic extripation of gastric submucosal tumor. Stomach and Intestine 1976;11:1475–1484 (in Japanese)Google Scholar
  4. 4.
    Eda Y, Yamagata L, Kanazaswa N, et al: A case report: Endoscopic Resection of a Granular cell Tumor of the stomach. Gastroenterological Endoscopy 1988;30(9):Sep (in Japanaese)Google Scholar
  5. 5.
    Seremetis MG, Lyons WS, deGuzman VC, et al: Leiomyomata of the esophagus — an analysis of 838 cases. Cancer 1976;38:2166–2177PubMedCrossRefGoogle Scholar
  6. 6.
    Seifert E, Elstev K: Gastric polypectomy Am J Gastroenterol 1975;63:451–456PubMedGoogle Scholar
  7. 7.
    Asaki S, Hatori S, Iwai S, et al: Diagnosis of Submucosal tumors by injecting a Water Soluble Contrast Medium: Basic Research and Imaging of Tumors; Tohoku J Exp Med 1982;138:121–130PubMedCrossRefGoogle Scholar
  8. 8.
    Asaki S, Nishimura T, Ohara S, et al: New trial of Endoscopic Treatment for Gastric Submucosal tomors; Tohoku J Exp Med 1985;145:149–159PubMedGoogle Scholar
  9. 9.
    Asaki S, Hatori S, Nishimura T, et al: Diagnosis of Submucosal tumors by injecting a Water Soluble Contrast Medium: Development Pattern and Growing of Tumors. Tohoku J Exp Med 1984;143:385–395PubMedGoogle Scholar
  10. 10.
    Robinson AS, Sommer DA, Levinson M: Transfiberscopic removal of esophageal polyps. Am J Gastroenterol 1974:61:297–300PubMedGoogle Scholar
  11. 11.
    Kadian RS, Marshalll HE, Jacobs WH: The removal of an esophageal papilloma by endoscopic means. Am J Gastroenterol 1975;64:221–223PubMedGoogle Scholar
  12. 12.
    Ravry MJR: Endoscopic resection of squamous papilloma of the esophagus.; Am J Gastroenterol 1979:71:398–400PubMedGoogle Scholar
  13. 13.
    Jacobs WH, Bruns D: Endoscopic electrosurgical polypectmies of upper gastrointestinal tract. Am J Gastroenterol 1977:68:241–248PubMedGoogle Scholar
  14. 14.
    Faivre J, Bory R: Moulinier, Benign tumors of oesophagusvalue of enb-doscopy. Endoscopy 1978:10:264–268PubMedGoogle Scholar
  15. 15.
    Asaki S.Nishimura T, Satoh A, et al: Endoscopic Hemostasis of Gastrointestinal Hemorrhage by Local application of Absolute Ethanol: A Clinical Study Tohoku J Exp Med 1983:141:377–383Google Scholar
  16. 16.
    Asaki S: Tissure solidification in coping with Digestive Tract Bleeding: Hemostatic effect of local Injection of 99.5% Ethanol; Tohoku J Exp Med 1981:134:223–227PubMedGoogle Scholar

Copyright information

© The Japanese Society of Gastroenterology 1990

Authors and Affiliations

  • Yoshiki Eda
    • 1
  • Shigeru Asaki
    • 1
  • Lin Yamagata
    • 2
  • Shuichi Ohara
    • 1
  • Daisuke Shibuya
    • 1
  • Takayoshi Toyota
    • 1
  1. 1.Third Department of Internal MedicineTohoku University school of MedicineSendaiJapan
  2. 2.Department of GastroenterologyTohoku-Rosai HospitalSendaiJapan

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