Summary
A solitary pedunculated gastric polyp in the gastric fundus was removed from an asymptomatic 36-year-old woman with normal gastric acid secretion and a normal serum gastrin level. This lesion exhibited distinctive histological features including prominent proliferation of pseudopyloric glands, fundic glands, foveolar epithelium and a fibromuscular stroma. Moreover, its surface was entirely covered by a layer of normal gastric epithelium. Biopsies of the background mucosa taken from the gastric fundus revealed only mild superficial gastritis. A gastric gland heterotopia was diagnosed because of its unique morphology.
Similar content being viewed by others
References
Ming SG, Goldman H. Gastric polyps; A histogenetic classification and its relation to carcinoma Cancer 1965;18:721–726.
Ming SG. The classification and significance of gastric polyps. In: Yardley JH, Morson BC, Abell MR, eds. International academy of pathology monography series: The gastrointestinal tract. Baltimore: Waverly Press, Inc., 1977;149–175.
Tomasulo J. Gastric polyps; histologic types and their relationship to gastric carcinoma. Cancer 1971;27:1346–1355.
Elster K. Histologic classification of gastric polyps. Curr Top Pathol 1976;63:77–93.
Snover DC. Benign epithelial polyps of the stomach. Pathol Annu 1985;21:303–329.
Burdic D, Prior JT, Scanlon GT. Peutz-Jeghers’ syndrome; A clinicopathological study of a large family with a 10-year follow-up. Cancer 1963;16:854–867.
Dawson I. Hamartomas in the alimentary tract. Gut 1969;10:691–694.
Rintala A. The histological appearance of gastrointestinal polyps in the Peutz-Jeghers’ syndrome. Acta Chir Scandinav 1959;117:366–373.
Carfagna G, Pilato FP, Bordi C. Solitary polypoid hamartoma of the oxyntic mucosa of the stomach. Pathol Res Pract 1981;182: 326–330.
Hanada M, Takami M, Kazuya H, et al. Hyperplastic fundic gland polyp of the stomach. Acta Pathol Jpn 1983;33:1269–1277.
Tatsuta M, Saegusa T, Okuda S. Studies on gastritis in the upper portion of stomach by endoscopic Congo Red test. Endoscopy 1973;5:61–69.
Ito H, Hata J, Yokozaki H, et al. Tubular adenoma of the human stomach—an immunohistochemical analysis of gut hormones, serotonin, carcinoembryonic antigen, secretory component, and lysozyme. Cancer 1986;58:2264–2272.
Davis GR. Gastric polyps. In: Sleisenger MH, Fordtran JS, eds. Gastrointestinal disease, 4th ed. Philadelphia: WB Saunders Co., 1989;763–764.
Nelson RS, Lanza FL. Hyperplastic polyps. In: Berk JE, Haubrich WS, Kaiser MH, Roth JLA, Schaffner F, eds. Bockus, Gastroenterology, 4th ed. Philadelphia: WB Saunders Co., 1985;2:1255–1257.
Sakurada H, Ishima A, Arakawa H, et al. Comparative study on gastric secretory function between benign gastric polyp and elevated type of early stomach cancer with special reference to histological findings of gastric mucosa. Tohoku J Exp Med 1976; 118(suppl):39–43.
Siurala M, Lehtola J, Ihamaki T. Atrophie gastritis and its sequelae. Scand J Gastroenterol 1974;9:441–446.
Elsborg L, Ardersen D, Gastrup-madsen P. Gastrocamera screening in pernicious anemia with special reference to the occurrence of gastric polyps and cancer. Scand J Gastroenterol 1973;8:5–8.
Haruma K, Sumii K, Kimura M, et al. Gastric mucosa in patients with foveolar hyperplastic polyps—with special reference to gastric acid secretion, serum gastrin level, and serum pepsinogen I level. Gastroenterological Endoscopy 1989;31:2051–2059 (in Japanese with English abstract).
Kuwano H, Takano H, Sugimachi K. Solitary Peutz-Jeghers’ type polyp of the stomach in the absence of Familial Polyposis Coli in a teenage boy. Endoscopy 1989;21:188–190.
Horn RC, Payne WA, Fine F. The Peutz-Jeghers’ syndrome (gastrointestinal polyposis with mucocutaneous pigmentation): report of a case terminating with disseminated gastrointestinal cancer. Arch Pathol 1963;76:29–37.
Hara M, Tsutsumi Y, Watanabe K, et al. Solitary gastric polyps in the fundic gland area, A histochemical study. Acta Pathol Jpn 1985;35:835–840.
Watanabe H, Jass JR, Sobin LH. Gastric Gland Heterotopia. In: Watanabe H, Jass JR, Sobin LH in Collaboration with Pathologists in 8 Countries, eds. Histological Typing of Oesophageal and Gastric Tumours. New York: Springer-Verlag, 1990;35–36.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hou, W., Haruma, K., Sumii, K. et al. Solitary pedunculated polypoid gastric gland heterotopia. Gastroenterol Jpn 28, 415–419 (1993). https://doi.org/10.1007/BF02776987
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02776987