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Gastroenterologia Japonica

, Volume 10, Issue 1, pp 29–34 | Cite as

Studies on the etiology of milk intolerance in Japanese adults

  • Yutaka Yoshida
  • Giro Sasaki
  • Shohei Goto
  • Shigetoshi Yanagiya
  • Kazuo Takashina
Original Article

Summary

  1. 1.

    The incidence of milk intolerance is approximately 19% in Japanese adults when 200 ml of milk is given. However, a much greater incidence was assumed when considered under the criteria of Western standard.

     
  2. 2.

    The lactase activity was significantly greater in milk drinkers than non-drinkers. And, internation ally, the activity is higher in those nationalities whose milk consumption is greater.

     
  3. 3.

    Lactase is an adaptive enzyme and rather easily induced by lactose load feeding in animals. From the data of our own and of the literature, it was further confirmed that environmental factors play a more important role than genetic factors in the etio-pathogenesis of milk intolerance.

     

Key words

milk intolerance primary adult hypolactasia disaccharidase lactase lactose load feeding 

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Copyright information

© The Japanese Society of Gastroenterology 1975

Authors and Affiliations

  • Yutaka Yoshida
    • 1
    • 2
  • Giro Sasaki
    • 1
  • Shohei Goto
    • 1
  • Shigetoshi Yanagiya
    • 1
  • Kazuo Takashina
    • 1
  1. 1.First Department of Internal MedicineHirosaki University School of MedicineJapan
  2. 2.1st Department of Internal MedicineHirosaki University School of MedicineHirosaki CityJapan

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