Gastric acid secretion in a child with postbulbar duodenal ulcer
- 11 Downloads
A 14-year-old case was reported with a primary postbulbar duodenal ulcer, which was confirmed by barium meal study and duodenoscopy. In the preoperative study, the patient showed marked gastric hyperacidity: maximal and peak acid output were 0.980 and 1.434 mEq/kg/hr, respectively. As previously described, hyperacidity appears to be a main factor in the pathogenesis of postbulbar duodenal ulcer. Fasting and postprandial serum gastrin secretion was not thought to be responsible for gastric hyperacidity in the present case. Upon histological investigation, the operatively resected stomach did not suggest a possible relationship between hyperacidity and an enlarged parietal cell mass.
Key wordschild gastric acid gastritis parietal cell postbulbar duodenal ulcer
Unable to display preview. Download preview PDF.
- 1.Ramos AR, Kirsner JB, Palmer WL: Peptic ulcer in children. AMA J Dis Child 1960;99:135–148Google Scholar
- 3.Kawai K, Kohli Y, Fujisawa T: X-ray diagnosis of postbulbar duodenal ulcer by means of double air contrast method. Gastroenterol Jpn 1970;5:293–298Google Scholar
- 5.Roth JLA, Stein GN, Morrissey JF, et al: Diagnosis of peptic ulcer. In: Berk JE, Haubrich WS, Kaiser MH, eds. Gastroenterology Vol. 2. WB Saunders, Philadelphia. 1985;1060–1115Google Scholar
- 6.Ritchie JD: Postbulbar duodenal ulcer. Aust NZ J Surg 1976;46:116–120Google Scholar
- 7.Portis SA, Jáffe RH: Study of peptic ulcer based on necropsy records. JAMA 1938;110:6–12Google Scholar
- 9.Sturtevant M, Shapiro LL: Gastric and duodenal ulcer. Arch Intern Med 1926;38:41–56Google Scholar
- 17.Ramsdell JA, Bartholomew LG, Cain JC, et al: Postbulbar duodenal ulcer. Ann Intern Med 1957;46:700–710Google Scholar