Gastroenterologia Japonica

, Volume 15, Issue 5, pp 452–463 | Cite as

Validity of long-term recordings of electrical activity of the stomach by chronically implanted monopolar suction electrodes in the conscious dog

  • Yasunori Atobe
  • Masanobu Akagi
  • Katsuhide Nishi
Original Article


Twenty-four-hour changes in gastric electrical activity were recorded in conscious dogs by means of chronically implanted monopolar suction electrodes. The electrical activity consisted of an initial potential followed by a second potential with various amplitude and duration depending upon the time after feeding. Amplitude of the second potential was well correlated to magnitude of each contraction. Characteristics of the electrical activity were qualitatively similar to those obtained with the intracellular microelectrode technique. 24-hour changes in cycles of electrical activity were divided into four phases; the first phase (lasting for 2–4 hours after feeding) characterized by a significant decrease in the cycle, the second phase (until 6–8 hours after feeding) in which the cycle gradually increased, the third phase (10–16 hours after feeding), and the last phase (lasting to the next meal), showing a marked variation in the cycle. These changes occurred irrespectively at the time of feeding and were consistent day after day as long as the animals were held on a constant feeding schedule. The recording method was suitable for recording gastric electrical activity which would provide more precise informations occurring in the intracellular electrical activity of the stomach in a long period of time under a physiological condition.

Key Words

conscious dog implanted suction electrode stomach electromyography 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1).
    Alvarez WC, et al: Action currents in stomach and intestine. AmJ Physiol 58: 476, 1921Google Scholar
  2. 2).
    Allen GL, et al: Relationships between electrical activities of antrum and duodenum. Am J Physiol 207: 906, 1964PubMedGoogle Scholar
  3. 3).
    Bass P, et al: Electric activity of gastroduodenal junction. AmJ Physiol 201: 587, 1961Google Scholar
  4. 4).
    Bozler E: The action potential of the stomach. Am J Physiol 144: 693, 1945Google Scholar
  5. 5).
    Daniel EE, et al: Electrical activity of the gastrointestinal tract as an indication of mechanical activity. Am J Dig Dis 8: 54, 1963PubMedCrossRefGoogle Scholar
  6. 6).
    Daniel EE: The electrical and contractile activity of the pyloric region in dogs and the effects of drugs. Gastroenterology 49: 403, 1965PubMedGoogle Scholar
  7. 7).
    Kelly KA, et al: Patterns of canine gastric electrical activity. AmJ Physiol 217: 461, 1969Google Scholar
  8. 8).
    McCoy EJ, et al: Chronic electrical activity of gastroduodenal area: Effects of food and certain catecholamines. Am J Physiol 205: 439, 1963PubMedGoogle Scholar
  9. 9).
    Papasova MP, et al: Two-component slow waves in smooth muscle of cat stomach. Am J Physiol 214: 695, 1968PubMedGoogle Scholar
  10. 10).
    Sakamoto S, et al: Electrical and mechanical activities in the stomach of the dog: Effects of the vagus nerve stimulation, atropine, neostigmine and adrenaline. Kumamoto Medical J 20: 25, 1967Google Scholar
  11. 11).
    Code CF, et al: The interdigestive myo-electric complex of the stomach and small bowel of dogs. J Physiol 246: 289, 1975PubMedGoogle Scholar
  12. 12).
    El-Sharkawy TY, et al: Intracellular electrical activity of canine and human gastric smooth muscle. J Physiol 279: 291, 1978PubMedGoogle Scholar
  13. 13).
    El-Sharkawy TY, et al: Modulation of canine antral circular smooth muscle by acethylcholine, noradrenaline and pentagastrin. J Physiol 279: 309, 1978PubMedGoogle Scholar
  14. 14).
    Bortoff A, et al: Transmission of electrical activity through the gastroduodenal junction. Am J Physiol 208: 531, 1965PubMedGoogle Scholar
  15. 15).
    Bass P, et al: Contractile force transducer for recording muscle activity in unanesthetized animals. J Appl Physiol 32: 567, 1972PubMedGoogle Scholar
  16. 16).
    Reinke DA, et al: Patterns of dog gastrointestinal contractile activity monitored in vivo with extraluminal force transducers. Am J Dig Dis 12: 113, 1967PubMedCrossRefGoogle Scholar
  17. 17).
    Itoh Z, et al: An extraluminal force transducer for recording contractile activity of the gastrointestinal smooth muscle in the conscious dogs: Its construction and implantation. Gastroenterologica Japonica 12: 275, 1977PubMedGoogle Scholar
  18. 18).
    Hoffman BF, et al: Comparison of cardiac monophasic action potentials recorded by intracellular and suction electrodes. Am J Physiol 196: 1297, 1959PubMedGoogle Scholar
  19. 19).
    Szurszewski JH: Mechanism of action of pentagastrin and acetylcholine on the longitudinal muscle of the canine antrum. J Physiol 252: 335, 1975PubMedGoogle Scholar
  20. 20).
    Duthie HL, et al: Pacesetter potential of the human gastroduodenal junction. Gut 12: 250, 1971PubMedCrossRefGoogle Scholar
  21. 21).
    Kelly KA: Effect of gastrin on gastric myo-electric activity. Am J Dig Dis 15: 399, 1970PubMedCrossRefGoogle Scholar
  22. 22).
    Nelsen TS, et al: Clinical electrogastrography and its relationship to gastric surgery. Am J Surg 116: 215, 1968PubMedCrossRefGoogle Scholar
  23. 23).
    Rosenquist CJ, et al: Electrical, contractile, and radiographic studies of the stomach after proximal gastric vagotomy. Am J Surg 134: 338, 1977PubMedCrossRefGoogle Scholar
  24. 24).
    Carlson GM, et al: Mechanism of propagation of intestinal interdigestive myoelectric complex. Am J Physiol 222: 1027, 1972PubMedGoogle Scholar
  25. 25).
    Grivel ML, et al: The propagation of segmental contractions along the small intestine. J Physiol 227: 611, 1972PubMedGoogle Scholar
  26. 26).
    Szurszewski JH, et al: Activity fronts of the canine small intestine. Gastroenterology 54: 1304, 1968Google Scholar
  27. 27).
    Surszewski JH: A migrating electric complex of the canine small intestine. Am J Physiol 217: 1757, 1969Google Scholar
  28. 28).
    Itoh Z, et al: Diurnal changes in gastric motor activity in conscious dogs. Am J Dig Dis 22: 117, 1977PubMedCrossRefGoogle Scholar

Copyright information

© The Japanese Society of Gastroenterology 1980

Authors and Affiliations

  • Yasunori Atobe
    • 1
  • Masanobu Akagi
    • 1
  • Katsuhide Nishi
    • 2
  1. 1.The Second Department of SurgeryKumamoto University Medical SchoolKumamotoJapan
  2. 2.The Second Department of PharmacologyKumamoto University Medical SchoolJapan

Personalised recommendations