Effects of synthetic C-terminal fragment of interferon-2α on Daudi cells
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Synthetic fragment of human interferon-2α (124th–138th amino acid residue, laboratory code 2438) inhibits the growth of B lymphocytes (Daudi cell line) in a dose-dependent manner. Radiolabeled peptide 2438 binds to specific receptors on the cell surface and competes with interferon-2α for the common binding sites.
Key Wordsinterferon peptide proliferation binding receptors
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