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Bilateral serous cystadenofibromas clinically simulating hyperreactio luteinalis following controlled ovarian hyperstimulation and in vitro fertilization

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Summary

We report a case of bilateral serous cystadenofibromas clinically simulating hyperreactio luteinalis during a normal pregnancy resulting from controlled ovarian stimulation and in vitro fertilization. Incomplete regression at 2-year follow-up prompted surgical intervention. This case demonstrates that the clinical and sonographic features that have been associated with hyperreactio luteinalis are not specific for this condition and emphasizes the need for close clinical follow-up in all presumptive cases for which a histologic diagnosis has not been established.

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References

  1. Joshi R, Dunaif A: Ovarian disorder during pregnancy. Endocrinol Metab Clin North Am 1985;24:153–168

    Google Scholar 

  2. Wajda KJ, Lucas J, Marsh WL: Hyperreactio luteinalis. Arch Pathol Lab Med 1989;113:921–925

    PubMed  CAS  Google Scholar 

  3. Garcia-Bunuel R, Berek JS, Woodruff JD: Luteomas of pregnancy. Obstet Gynecol 1975;45:407–414

    PubMed  CAS  Google Scholar 

  4. Hatjis C: Nonimmunologic fetal hydrops associated with hyperreactio luteinalis. Obstet Gynecol 1985;65:11S-13S

    PubMed  CAS  Google Scholar 

  5. Levine S, Huffaker J, Jacobson J, Brodey P, Fisch A: Second-trimester spontaneous regression of theca lutein cysts. Obstet Gynecol 1982;60:124–126

    PubMed  CAS  Google Scholar 

  6. Fayes J, Bunch T, Miller G: Virilization in pregnancy associated with an ovarian serous cystadenoma. Am J Obstet Gynecol 1974;120:341–346

    Google Scholar 

  7. Rossing M, Daling J, Weiss N, Moore D, Self S: Ovarian tumors in a cohort of infertile women. N Engl J Med 1994;331:771–776

    Article  PubMed  CAS  Google Scholar 

  8. Harris R, Whittemore A, Itnyre J, Collaborative Ovarian Cancer Group: Characteristics relating to ovarian cancer risk; Collaborative analysis of 12 US case-control studies. III. Epithelial tumors of low malignant potential in white women. Am J Epidemiol 1992;136:1204–1211

    PubMed  CAS  Google Scholar 

  9. Whittemore A, Harris R, Itnyre J, Collaborative Ovarian Cancer Group: Characteristics relating to ovarian cancer risk: Collaborative analysis of 12 US case-control studies. II. Invasive epithelial cancers in white women. Am J. Epidemiol 1992;136:1184–1203

    PubMed  CAS  Google Scholar 

  10. Scully R: Tumors of the ovary and maldeveloped gonads.In Atlas of Tumor Pathology, Second Series. Washington, DC: Armed Forces Institute of Pathology, 1979

    Google Scholar 

  11. Mittal K, Zeleniuch-Jacquotte A, Cooper J, Demopoulos R: Contralateral ovary in unilateral ovarian carcinoma: A search of preneoplastic lesions. Int J Gynecol Pathol 1993;12:59–63

    Article  PubMed  CAS  Google Scholar 

  12. Montz F, Schlaerth J, Morow C: The natural history of theca lutein cysts. Obstet Gynecol 1988;72:247–251

    PubMed  CAS  Google Scholar 

  13. Schwartz PE: The role of tumor markers in the preoperative diagnosis of ovarian cysts. Clin Obstet Gynecol 1993;36(2):384–394

    Article  PubMed  CAS  Google Scholar 

  14. Ozaksit NO, Turhan, Oral H, Dogu N, Gokmen O: Relationship between serum CA 125 levels, endometrial thickness and corpus luteum function in different stages of ovarian activity. J Endocrinol Invest 1993;16:175–179

    PubMed  CAS  Google Scholar 

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Ditkoff, E.C., Tucker, T., Levine, R.U. et al. Bilateral serous cystadenofibromas clinically simulating hyperreactio luteinalis following controlled ovarian hyperstimulation and in vitro fertilization. J Assist Reprod Genet 14, 230–233 (1997). https://doi.org/10.1007/BF02766116

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  • DOI: https://doi.org/10.1007/BF02766116

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