Correlation between molecular heterogeneity of ceruloplasmin mRNA and ceruloplasmin isomers synthesized in rat liver
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Molecular heterogeneity of ceruloplasmin mRNA is studied in rat liver polyribosomes. Blot hybridization of RNA with cDNA reveals three molecular forms of ceruloplasmin mRNA differing in the chain length and structure of the 3′-regions. A correlation between these mRNAs and three isoforms of ceruloplasmin, which perform different functions in the copper transport, is established.
Key WordsmRNA ceruloplasmin isoforms rat liver
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